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How to get fromAppleton to Key Westby plane, bus (Flixbus, Greyhound), bus, train or car

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There are 6 ways to get from Appleton to Key West by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Appleton International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Key West International Airport (EYW)plane plane ATW - EYW
    6h 12m
    $169–685

  2. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    43h 1m
    $222–536

  3. Bus, train

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 11h
    $616–1,410

  4. Drive 1,657.8 mi

    1. Drive from Appleton to Key Westcar car 1,657.8 mi
    30h 31m
    $303–437

  5. Fly from Green Bay

    1. Fly from Green Bay (GRB) to Key West International Airport (EYW)plane plane GRB - EYW
    7h 43m
    $187–705

  6. Bus to General Mitchell International Airport, fly

    1. Take the bus from Appleton Amtrak Station to Milwaukee Airport Amtrak Bus Stopbus bus
    2. Fly from General Mitchell International Airport (MKE) to Key West International Airport (EYW)plane plane MKE - EYW
    9h 22m
    $245–1,166

Appleton to Key West by bus and foot

Calendar5Weekly Services
Duration43h 1mAverage Duration
Ticket$222Cheapest Price
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Questions & Answers

What companies run services between Appleton, WI, USA and Key West, FL, USA?

Delta, American Airlines, and United Airlines fly from Appleton International Airport (ATW) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Appleton Transit Center to N Roosevelt & 3rd Street via Chicago Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 43h 1m.

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