What is the cheapest way to get from Appleton to Mayo Clinic?

The cheapest way to get from Appleton to Mayo Clinic is to drive which costs $40 - $65 and takes 4h 42m.

What is the fastest way to get from Appleton to Mayo Clinic?

The fastest way to get from Appleton to Mayo Clinic is to fly and bus which takes 4h 41m and costs $110 - $450.

Is there a direct bus between Appleton and Mayo Clinic?

No, there is no direct bus from Appleton to Mayo Clinic. However, there are services departing from Oshkosh and arriving at Rochester via Milwaukee. The journey, including transfers, takes approximately 8h 58m.

How far is it from Appleton to Mayo Clinic?

The distance between Appleton and Mayo Clinic is 214 miles. The road distance is 233.2 miles.

How do I travel from Appleton to Mayo Clinic without a car?

The best way to get from Appleton to Mayo Clinic without a car is to bus which takes 8h 58m and costs $130 - $180.

How long does it take to get from Appleton to Mayo Clinic?

It takes approximately 4h 45m to get from Appleton to Mayo Clinic, including transfers.

Where do I catch the Appleton to Mayo Clinic bus from?

Appleton to Mayo Clinic bus services, operated by Lamers Bus Lines, depart from Oshkosh station.

Bus or fly from Appleton to Mayo Clinic?

The best way to get from Appleton to Mayo Clinic is to fly which takes 4h 45m and costs $60 - $380. Alternatively, you can bus, which costs $130 - $180 and takes 8h 58m.

Where does the Appleton to Mayo Clinic bus arrive?

Appleton to Mayo Clinic bus services, operated by Lamers Bus Lines, arrive at Milwaukee station.

Can I drive from Appleton to Mayo Clinic?

Yes, the driving distance between Appleton to Mayo Clinic is 233 miles. It takes approximately 4h 42m to drive from Appleton to Mayo Clinic.

Where can I stay near Mayo Clinic?

There are 77+ hotels available in Mayo Clinic.

Appleton to Mayo Clinic - 7 ways to travel via plane, bus, car, and taxi

There are 7 ways to get from Appleton to Mayo Clinic by plane, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly Appleton International Airport to Rochester
best
1. Fly from Appleton International Airport (ATW) to Rochester (RST)plane ATW - RST
4h 45m
$60–377
Drive 231.8 mi
cheapest
1. Drive from Appleton to Mayo Cliniccar 231.8 mi
4h 42m
$43–62
Bus
1. Take the bus from Oshkosh to Milwaukeebus Lab 211
2. Take the bus from Milwaukee to Rochesterbus Jefferson Lines 966
8h 58m
$138–180
Taxi to Green Bay, fly to Rochester
1. Take the taxi from Appleton to Green Bay (GRB)taxi
2. Fly from Green Bay (GRB) to Rochester (RST)plane GRB - RST
5h 17m
$150–487
Fly Appleton International Airport to Minneapolis–Saint Paul International Airport, bus
1. Fly from Appleton International Airport (ATW) to Minneapolis–Saint Paul International Airport (MSP)plane ATW - MSP
2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
4h 41m
$119–447
Taxi to Green Bay, fly to Minneapolis–Saint Paul International Airport, bus
1. Take the taxi from Appleton to Green Bay (GRB)taxi
2. Fly from Green Bay (GRB) to Minneapolis–Saint Paul International Airport (MSP)plane GRB - MSP
3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 10m
$204–547
Taxi, bus
1. Take the taxi from Appleton to Green Bay Transit Centertaxi
2. Take the bus from Green Bay Transit Center to Minneapolis Bus Stationbus
3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
10h 58m
$219–271

Appleton International Airport (ATW) to Rochester (RST) flights

63Weekly Planes

5h 10mAverage Duration

$49Cheapest Price

See schedules

Comparing Your Travel Options

Map of how to get from Appleton to Mayo Clinic.

Launch map view

Distance: 213.2 mi
Duration: 4h 45m

What companies run services between Appleton, WI, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Appleton International Airport (ATW) to Rochester (RST) every 3 hours. Alternatively, you can take a vehicle from Appleton to Mayo Clinic via Oshkosh, Milwaukee, and Rochester in around 8h 58m.

Airlines

Bus operators

Other operators

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How to get fromAppleton to Mayo Clinicby plane, bus, car, or taxi

There are 7 ways to get from Appleton to Mayo Clinic by plane, bus, car, or taxi

Fly Appleton International Airport to Rochester

Drive 231.8 mi

Bus

Taxi to Green Bay, fly to Rochester

Fly Appleton International Airport to Minneapolis–Saint Paul International Airport, bus

Taxi to Green Bay, fly to Minneapolis–Saint Paul International Airport, bus

Taxi, bus