There are 7 ways to get from Appleton to Mayo Clinic by plane, taxi, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Appleton International Airport to Rochester
best- Fly from Appleton International Airport (ATW) to Rochester (RST)plane ATW - RST
5h 16m$64–372Drive 232.6 mi
cheapest- Drive from Appleton to Mayo Cliniccar 232.6 mi
4h 30m$43–62Taxi, bus
- Take the taxi from Appleton to Green Bay Amtrak Stationtaxi
- Take the bus from Green Bay Amtrak Station to St. Paul-Minneapolisbus
- Take the bus from St. Paul to Rochesterbus
9h 9mTaxi to Green Bay, fly to Rochester
- Take the taxi from Appleton to Green Bay (GRB)taxi
- Fly from Green Bay (GRB) to Rochester (RST)plane GRB - RST
5h 52m$147–469Fly Appleton International Airport to Minneapolis–Saint Paul International Airport, bus
- Fly from Appleton International Airport (ATW) to Minneapolis–Saint Paul International Airport (MSP)plane ATW - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
4h 23m$99–485Taxi to Green Bay, fly to Minneapolis–Saint Paul International Airport, bus
- Take the taxi from Appleton to Green Bay (GRB)taxi
- Fly from Green Bay (GRB) to Minneapolis–Saint Paul International Airport (MSP)plane GRB - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
4h 55m$182–582Taxi, bus via Madison
- Take the taxi from Appleton to Green Bay Transit, WItaxi
- Take the bus from Green Bay Transit, WI to Madisonbus 105
- Take the bus from Madison to Rochesterbus
10h 29m$173–336
Appleton International Airport (ATW) to Rochester (RST) flights
Questions & Answers
The cheapest way to get from Appleton to Mayo Clinic is to drive which costs $40 - $65 and takes 4h 30m.
The fastest way to get from Appleton to Mayo Clinic is to fly and bus which takes 4h 23m and costs $95 - $490.
The distance between Appleton and Mayo Clinic is 214 miles. The road distance is 234 miles.
The best way to get from Appleton to Mayo Clinic without a car is to taxi and bus which takes 9h 9m and costs .
It takes approximately 5h 16m to get from Appleton to Mayo Clinic, including transfers.
Yes, the driving distance between Appleton to Mayo Clinic is 234 miles. It takes approximately 4h 30m to drive from Appleton to Mayo Clinic.
There are 78+ hotels available in Mayo Clinic.
What companies run services between Appleton, WI, USA and Mayo Clinic, MN, USA?
American Airlines, Delta, and United Airlines fly from Appleton International Airport (ATW) to Rochester (RST) every 4 hours.
- Website
- delta.com
Flights from Appleton International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $45–310
Flights from Green Bay to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $45–310
Flights from Appleton International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $60–440
Flights from Green Bay to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $60–440
- Website
- aa.com
Flights from Appleton International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $50–330
Flights from Green Bay to Rochester via Chicago O'Hare
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $50–340
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Green Bay Amtrak Station to St. Paul-Minneapolis
- Ave. Duration
- 6h
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $7–55
- Book at
- https://www.jeffersonlines.com
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $20–95
- Book at
- https://www.jeffersonlines.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $19–45
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
- Phone
- +1 800-236-1240
- Website
- golamers.com
Bus from Green Bay Transit, WI to Madison
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $30–95
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
- Ave. Duration
- 37 min
- Estimated price
- $100–150
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
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