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How to get fromAppleton to Saint Charlesby plane, bus, train, bus (Flixbus) or car

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There are 6 ways to get from Appleton to Saint Charles by plane, bus, train, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Appleton International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Lambert–St. Louis International Airport (STL)plane plane ATW - STL
    5h
    $122–676

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus N2521 / ...
    13h 5m
    $63–115

  3. Bus, train

    1. Take the bus from Appleton Amtrak Station to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    12h 3m
    $115–279

  4. Drive 457.3 mi

    1. Drive from Appleton to Saint Charlescar car 457.3 mi
    7h 50m
    $84–121

  5. Fly from Green Bay

    1. Fly from Green Bay (GRB) to Lambert–St. Louis International Airport (STL)plane plane GRB - STL
    6h 26m
    $140–696

  6. Bus to General Mitchell International Airport, fly

    1. Take the bus from Appleton Amtrak Station to Milwaukee Airport Amtrak Bus Stopbus bus
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    6h 20m
    $168–1,163

Appleton to Saint Charles by bus and train

Calendar26Weekly Services
Duration12h 3mAverage Duration
Ticket$115Cheapest Price
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Questions & Answers

What companies run services between Appleton, WI, USA and Saint Charles, MO, USA?

American Airlines, United Airlines, and Delta fly from Appleton International Airport (ATW) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Appleton Transit Center to 4375 Rider Trail North Sb via Chicago Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 13h 5m.

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