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How to get fromAppleton to Charlestonby plane, bus (Flixbus, Greyhound), bus, train or car

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There are 6 ways to get from Appleton to Charleston by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Charleston International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Charleston International Airport (CHS)plane plane ATW - CHS
    6h 28m
    $100–444
  2. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    34h 2m
    $160–276
  3. Bus, train

    1. Take the bus from Appleton Amtrak Station to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    34h 25m
    $261–510
  4. Drive 1,061.8 mi

    1. Drive from Appleton to Charlestoncar car 1,061.8 mi
    19h 22m
    $194–280
  5. Fly Green Bay to Charleston International Airport

    1. Fly from Green Bay (GRB) to Charleston International Airport (CHS)plane plane GRB - CHS
    7h 43m
    $118–474
  6. Fly Appleton International Airport to Hilton Head Airport, drive

    1. Fly from Appleton International Airport (ATW) to Hilton Head Airport (HHH)plane plane ATW - HHH
    2. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    8h 37m
    $116–469

Appleton to Charleston by bus

Calendar5Weekly Buses
Duration34h 2mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

What companies run services between Appleton, WI, USA and Charleston, SC, USA?

United Airlines, American Airlines, and Delta fly from Appleton International Airport (ATW) to Charleston International Airport (CHS) every 4 hours. Alternatively, you can take a bus from Appleton Transit Center to Transit Mall via Chicago Bus Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 34h 2m.

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