The average train between Wetzlar and Brussels takes 6h 40m and the fastest train takes 4h 54m. The train service runs several times per day from Wetzlar to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Wetzlar and Brussels. The earliest departure is at 8:32 AM in the morning, and the last departure from Wetzlar is at 8:32 PM which arrives into Brussels at 9:26 AM. All services require a transfer at Gießen Bahnhof and take an average of 6h 40m. The schedules shown below are for the next available departures.


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Want to know about travelling from Wetzlar to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Brussels. However, there are services departing from Wetzlar station and arriving at Brussels station via Frankfurt. The journey, including transfers, takes approximately 6h 40m.
Wetzlar to Brussels train services, operated by Deutsche Bahn Regio (DB Regional), depart from Gießen Bahnhof station.
Wetzlar to Brussels train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Brussels-Nord station.
Book your Wetzlar to Brussels train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Wetzlar and Brussels is 294.4 km. The road distance is 474 km.
You can take a train from Wetzlar Bahnhof to Brussels-Nord via Gießen Bahnhof and Frankfurt in around 5h 45m.