The average train between Wetzlar and Mannheim takes 3h 6m and the fastest train takes 2h 45m. The train service runs several times per day from Wetzlar to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Wetzlar and Mannheim. The earliest departure is at 6:44 AM in the morning, and the last departure from Wetzlar is at 8:32 PM which arrives into Mannheim at 11:29 PM. All services require a transfer at Gießen Bahnhof and take an average of 3h 6m. The schedules shown below are for the next available departures.


3h 6m • 2 changes

3h 25m • 2 changes

3h 25m • 2 changes

3h 4m • 2 changes

3h 6m • 2 changes

3h 25m • 2 changes

3h 25m • 2 changes

3h 25m • 2 changes

2h 45m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 45m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 45m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 45m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changes

2h 57m • 2 changesWant to know about travelling from Wetzlar to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wetzlar to Mannheim. However, there are services departing from Wetzlar station and arriving at Mannheim station via Frankfurt. The journey, including transfers, takes approximately 3h 6m.
Wetzlar to Mannheim train services, operated by Deutsche Bahn Regio (DB Regional), depart from Gießen Bahnhof station.
Wetzlar to Mannheim train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Book your Wetzlar to Mannheim train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Wetzlar and Mannheim is 119.2 km. The road distance is 156 km.
You can take a train from Wetzlar Bahnhof to Mannheim, Hauptbahnhof via Gießen Bahnhof and Frankfurt in around 2h 54m.