The average train between Manchester and Brussels takes 5h 15m and the fastest train takes 4h 20m. The train service runs several times per day from Manchester to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Manchester and Brussels. The earliest departure is at 6:30 AM in the morning, and the last departure from Manchester is at 10:15 PM which arrives into Brussels at 10:05 AM. All services require a transfer at London Euston and take an average of 5h 15m. The schedules shown below are for the next available departures.

5h 34m • 1 change

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Want to know about travelling from Manchester to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Brussels. However, there are services departing from Manchester station and arriving at Brussels station via London Euston. The journey, including transfers, takes approximately 5h 15m.
Manchester to Brussels train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Brussels train services, operated by Avanti West Coast, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Manchester to Brussels train tickets online with Avanti West Coast and Eurostar.
The distance between Manchester and Brussels is 535.7 km. The road distance is 666 km.
You can take a train from Manchester Piccadilly to Brussel-Zuid / Bruxelles-Midi via London Euston and London St Pancras Intl in around 5h 18m.