The average train between Wesel and Mainz takes 3h 10m and the fastest train takes 2h 33m. There is a train service every few hours from Wesel to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Wesel and Mainz. The earliest departure is at 3:43 AM at night, and the last departure from Wesel is at 10:07 PM which arrives into Mainz at 1:23 AM. All services require a transfer at Duisburg Hbf and take an average of 3h 10m. The schedules shown below are for the next available departures.


3h 40m • 2 changes


3h 40m • 2 changes


2h 37m • 2 changes


3h 16m • 2 changes


3h 40m • 2 changes


3h 40m • 2 changes


3h 16m • 2 changes


3h 16m • 2 changes


3h 39m • 2 changes


3h 15m • 2 changes


2h 37m • 2 changes


2h 59m • 2 changes
Want to know about travelling from Wesel to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Wesel to Mainz. However, there are services departing from Wesel station and arriving at Mainz station via Duisburg Hbf. The journey, including transfers, takes approximately 3h 10m.
Wesel to Mainz train services, operated by VIAS Rail GmbH, depart from Wesel station.
Wesel to Mainz train services, operated by VIAS Rail GmbH, arrive at Frankfurt station.
Book your Wesel to Mainz train tickets online with VIAS Rail GmbH, Deutsche Bahn Intercity (DB IC) and 4 other operators.
The distance between Wesel and Mainz is 220.4 km. The road distance is 289 km.
You can take a train from Wesel to Mainz, Römisches Theater via Duisburg Hbf and Frankfurt in around 2h 55m.