The average train between Leipzig and Mainz takes 4h 33m and the fastest train takes 3h 37m. There is a train service every few hours from Leipzig to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Leipzig and Mainz. The earliest departure is at 5:28 AM in the morning, and the last departure from Leipzig is at 10:58 PM which arrives into Mainz at 2:53 AM. All services require a transfer, and take on average 4h 33m. The schedules shown below are for the next available departures.

4h 55m • 1 change

4h 27m • 1 change

4h 56m • 1 change

4h • 1 change

4h 55m • 1 change

4h 34m • 1 change

4h 56m • 1 change

4h 4m • 1 change

4h 54m • 1 change

4h 33m • 1 change

4h 55m • 1 change

4h 3m • 1 change
Want to know about travelling from Leipzig to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Leipzig to Mainz. However, there are services departing from Leipzig station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 4h 33m.
Leipzig to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Leipzig Hbf station.
Leipzig to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Leipzig to Mainz train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and 2 other operators.
The distance between Leipzig and Mainz is 325.4 km. The road distance is 475 km.
Deutsche Bahn Intercity (DB IC) operates a train from Leipzig Hbf to Frankfurt hourly. Tickets cost €75–220 and the journey takes 4h 2m.