The average train between Slough and Prescot takes 4h 14m and the fastest train takes 3h 30m. There is a train service every few hours from Slough to Prescot. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Slough and Prescot. The earliest departure is at 5:38 AM in the morning, and the last departure from Slough is at 8:52 PM which arrives into Prescot at 6:04 AM. All services require a transfer at Tottenham Court Road Station and take an average of 4h 14m. The schedules shown below are for the next available departures.



3h 56m • 3 changes



3h 49m • 3 changes



3h 49m • 3 changes



3h 49m • 3 changes



3h 56m • 3 changes



3h 49m • 3 changes



3h 49m • 3 changes



3h 49m • 3 changes



3h 56m • 3 changes



3h 49m • 3 changes



3h 49m • 3 changes



3h 49m • 3 changes
Want to know about travelling from Slough to Prescot? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Prescot. However, there are services departing from Slough station and arriving at Prescot station via Liverpool Lime Street. The journey, including transfers, takes approximately 4h 14m.
Slough to Prescot train services, operated by Elizabeth Line (TfL), depart from London Euston station.
Slough to Prescot train services, operated by Elizabeth Line (TfL), arrive at Liverpool Lime Street station.
Book your Slough to Prescot train tickets online with Elizabeth Line (TfL), London Underground (Tube) and 2 other operators.
The distance between Slough and Prescot is 260.5 km. The road distance is 357 km.
Avanti West Coast operates a train from London Euston to Liverpool Lime Street hourly. Tickets cost £65–120 and the journey takes 2h 21m.