The average train between Slough and Ayr takes 7h 30m and the fastest train takes 6h 28m. There is a train service every few hours from Slough to Ayr. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Slough and Ayr. The earliest departure is at 6:21 AM in the morning, and the last departure from Slough is at 11:21 PM which arrives into Ayr at 11:56 AM. All services require a transfer at Tottenham Court Road Station and take an average of 7h 30m. The schedules shown below are for the next available departures.



7h 1m • 3 changes



7h 2m • 3 changes



7h 2m • 3 changes



7h 3m • 3 changes



7h 35m • 3 changes



6h 59m • 3 changes



7h • 3 changes



7h 32m • 3 changes



6h 48m • 3 changes



6h 47m • 3 changes



6h 46m • 3 changes



6h 46m • 3 changes



6h 48m • 3 changes



6h 47m • 3 changes



6h 46m • 3 changes



6h 46m • 3 changes
Want to know about travelling from Slough to Ayr? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Ayr. However, there are services departing from Slough station and arriving at Ayr station via Glasgow Central. The journey, including transfers, takes approximately 7h 30m.
Slough to Ayr train services, operated by Elizabeth Line (TfL), depart from London Euston station.
Slough to Ayr train services, operated by Elizabeth Line (TfL), arrive at Ayr station.
Book your Slough to Ayr train tickets online with Elizabeth Line (TfL), London Underground (Tube) and 3 other operators.
The distance between Slough and Ayr is 514.2 km. The road distance is 741 km.
You can take a train from Slough to Ayr via Tottenham Court Road Station, Tottenham Court Road station, Euston station, London Euston, and Glasgow Central in around 7h 4m.