The average train between London and Prescot takes 3h 20m and the fastest train takes 2h 38m. There is a train service every few hours from London to Prescot. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between London and Prescot. The earliest departure is at 5:31 AM in the morning, and the last departure from London is at 9:10 PM which arrives into Prescot at 6:00 AM. All services require a transfer, and take on average 3h 20m. The schedules shown below are for the next available departures.

3h 17m • 1 change

2h 43m • 1 change
Arrives next day

9h 7m • 1 change

3h 15m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 38m • 1 change

3h 15m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 38m • 1 change

3h 15m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 38m • 1 change
Want to know about travelling from London to Prescot? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from London to Prescot. However, there are services departing from London station and arriving at Prescot station via Wigan North Western. The journey, including transfers, takes approximately 3h 20m.
London to Prescot train services, operated by Avanti West Coast, depart from London Euston station.
London to Prescot train services, operated by Avanti West Coast, arrive at Wigan North Western station.
Book your London to Prescot train tickets online with Avanti West Coast and Northern Trains Limited.
The distance between London and Prescot is 280.1 km. The road distance is 330 km.
Avanti West Coast operates a train from London Euston to Wigan North Western hourly. Tickets cost £65–120 and the journey takes 1h 54m.