The average train between Siena and Roma Termini takes 4h 2m and the fastest train takes 3h 8m. There is a train service every few hours from Siena to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Siena and Roma Termini. The earliest departure is at 6:25 AM in the morning, and the last departure from Siena is at 9:40 PM which arrives into Roma Termini at 7:49 AM. All services require a transfer, and take on average 4h 2m. The schedules shown below are for the next available departures.

3h 31m • 1 change

3h 31m • 1 change

3h 31m • 1 change

3h 52m • 1 change

3h 8m • 1 change

3h 49m • 1 change

3h 47m • 1 change

3h 31m • 1 change

3h 39m • 1 change

3h 34m • 1 change

3h 31m • 1 change

3h 27m • 1 change

3h 39m • 1 change

3h 34m • 1 change

3h 31m • 1 change

3h 27m • 1 change
Want to know about travelling from Siena to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Roma Termini. However, there are services departing from Siena station and arriving at Roma Termini station via Firenze S.M.N.. The journey, including transfers, takes approximately 4h 2m.
Siena to Roma Termini train services, operated by Trenitalia, depart from Siena station.
Siena to Roma Termini train services, operated by Trenitalia, arrive at Roma Termini station.
Book your Siena to Roma Termini train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Siena and Roma Termini is 184.4 km. The road distance is 354 km.
You can take a train from Siena to Roma Termini via Firenze S.M.N. in around 3h 32m.