Train Siena to Milan from €64 | Tickets & Timetables

Trip Overview

The average train between Siena and Milan takes 4h 52m and the fastest train takes 3h 25m. There is a train service every few hours from Siena to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 52m
Duration: 397 km
Distance: €64
Average price: Hourly
Frequency

Train (Trenitalia)

best

Take the train from Siena to Firenze S.M.N.train Re / ...
Take the train from Firenze S.M.N. to Milano Centraletrain Fr

4h 17m

€42–105

Siena to Milan train times

Trains run hourly between Siena and Milan. The earliest departure is at 6:25 AM in the morning, and the last departure from Siena is at 9:40 PM which arrives into Milan at 8:50 AM. All services require a transfer, and take on average 4h 52m. The schedules shown below are for the next available departures.

Departing Sunday, April 5, 2026

7:15 AM → 11:50 AM
4h 35m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
12:18 PM → 4:50 PM
4h 32m • 1 change
1:18 PM → 5:50 PM
4h 32m • 1 change
Show more

Departing Monday, April 6, 2026

6:36 AM → 10:50 AM
4h 14m • 1 change
7:15 AM → 11:50 AM
4h 35m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
12:18 PM → 4:50 PM
4h 32m • 1 change
Show more

Departing Tuesday, April 7, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Departing Wednesday, April 8, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Departing Thursday, April 9, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change

Frequently asked questions

Want to know about travelling from Siena to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.