Siena to Milan Trains

Siena to Milan trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Siena and Milan takes 4h 50m and the fastest train takes 3h 25m. There is a train service every few hours from Siena to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 50m
Duration: 397 km
Distance: €58
Average price: Hourly
Frequency

Train

best

Take the train from Siena to Firenze S.M.N.train Re / ...
Take the train from Firenze S.M.N. to Milano Centraletrain Fr

3h 50m

€41–90

Siena to Milan train times

Trains run hourly between Siena and Milan. The earliest departure is at 6:25 AM in the morning, and the last departure from Siena is at 9:40 PM which arrives into Milan at 8:50 AM. All services require a transfer, and take on average 4h 50m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Departing Saturday, October 24, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Departing Sunday, October 25, 2026

6:36 AM → 10:50 AM
4h 14m • 1 change
7:15 AM → 11:50 AM
4h 35m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
12:18 PM → 4:50 PM
4h 32m • 1 change
Show more

Departing Monday, October 26, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Departing Tuesday, October 27, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Departing Wednesday, October 28, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Departing Thursday, October 29, 2026

6:25 AM → 9:50 AM
3h 25m • 1 change
6:36 AM → 10:50 AM
4h 14m • 1 change
7:02 AM → 11:50 AM
4h 48m • 1 change
8:48 AM → 12:50 PM
4h 2m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Siena to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.