Bus Siena to Roma Termini from €25 | Tickets & Timetables

Trip Overview

The average bus between Siena and Roma Termini takes 3h 21m and the fastest bus takes 2h 59m. The bus service runs several times per day from Siena to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 21m
Duration: 234 km
Distance: €25
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Siena to Roma, Autostazione Tiburtinabus 1520 / ...

3h 18m

€17–34

Siena to Roma Termini bus times

Buses run every 3 hours between Siena and Roma Termini. The earliest departure is at 5:35 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Roma Termini at 2:05 AM. All services require a transfer, and take on average 3h 21m. The schedules shown below are for the next available departures.

Departing Sunday, May 24, 2026

7:45 PM → 11:11 PM
3h 26m • 1 change
9:00 PM → 12:11 AM
Arrives next day
3h 11m • 1 change
10:25 PM → 1:37 AM
Arrives next day
3h 12m • 1 change

Departing Monday, May 25, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change
8:45 AM → 12:06 PM
3h 21m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
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Departing Tuesday, May 26, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change
8:45 AM → 12:06 PM
3h 21m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
Show more

Departing Wednesday, May 27, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change
8:45 AM → 12:06 PM
3h 21m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
Show more

Departing Thursday, May 28, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change
8:45 AM → 12:06 PM
3h 21m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
Show more

Departing Friday, May 29, 2026

5:35 AM → 9:10 AM
3h 35m • 1 change
7:00 AM → 10:23 AM
3h 23m • 1 change
8:45 AM → 12:06 PM
3h 21m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
Show more

Departing Saturday, May 30, 2026

5:35 AM → 9:04 AM
3h 29m • 1 change
7:00 AM → 10:28 AM
3h 28m • 1 change
8:45 AM → 11:53 AM
3h 8m • 1 change
10:45 AM → 2:02 PM
3h 17m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Siena to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.