The average train between Siena and Palermo takes 19h 4m and the fastest train takes 15h 43m. The train service runs several times per day from Siena to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Siena and Palermo. The earliest departure is at 7:02 AM in the morning, and the last departure from Siena is at 8:18 PM which arrives into Palermo at 7:04 PM. All services require a transfer at Firenze S.M.N. and take an average of 19h 4m. The schedules shown below are for the next available departures.
Want to know about travelling from Siena to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Palermo. However, there are services departing from Siena station and arriving at Palermo Centrale station via Firenze S.M.N. station and Roma Termini station. The journey, including transfers, takes approximately 19h 4m.
Siena to Palermo train services, operated by Trenitalia, depart from Siena station.
Siena to Palermo train services, operated by Trenitalia Intercity, arrive at Palermo Centrale station.
Book your Siena to Palermo train tickets online with Omio.
The distance between Siena and Palermo is 600.9 km.
You can take a train from Siena to Palermo Centrale via Firenze S.M.N. and Roma Termini in around 15h 50m.