The train between Siena and Palermo takes 22h 50m. The train runs, on average, 6 times per week from Siena to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 6 times a week between Siena and Palermo. The earliest departure is at 8:18 PM in the evening, and the last departure from Siena is at 8:18 PM which arrives into Palermo at 7:08 PM. All services require a transfer at Firenze S.M.N. and take an average of 22h 50m. The schedules shown below are for the next available departures.
Want to know about travelling from Siena to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Palermo. However, there are services departing from Siena station and arriving at Palermo station via Firenze S.M.N.. The journey, including transfers, takes approximately 22h 50m.
Siena to Palermo train services, operated by Trenitalia, depart from Siena station.
Siena to Palermo train services, operated by Trenitalia, arrive at Palermo Centrale station.
Book your Siena to Palermo train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Siena and Palermo is 600.9 km. The road distance is 1,219 km.
You can take a train from Siena to Palermo Centrale via Firenze S.M.N. and Roma Termini in around 16h 11m.