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How to get fromSiena to Palermoby bus, plane, train (Trenitalia), train, ferry, car or car ferry

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There are 9 ways to get from Siena to Palermo by bus, plane, train (Trenitalia), train, ferry, car, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Florence Peretola Airport, fly

    best
    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus
    2. Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane plane FLR - PMO
    5h 6m
  2. Bus to Perugia Sant'Egidio Airport, fly

    cheapest
    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane plane PEG - PMO
    6h 25m
    €42–291
  3. Bus

    1. Take the bus from Siena to Palermobus bus N597
    16h
    €70–130
  4. Train (Trenitalia)

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    3. Take the train from Roma Termini to Palermo Centraletrain train Ic
    16h 24m
    €107–285
  5. Bus, train, ferry

    1. Take the bus from Siena-Via Tozzi to Grosseto F.S.bus bus 51G
    2. Take the train from Grosseto to Civitavecchiatrain train Re
    3. Take the ferry from Port of Civitavecchia to Port of Palermoferry ferry
    17h 14m
  6. Train, train to Pisa International Airport, fly

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    5h 41m
    €57–226
  7. Bus, train to Bologna Guglielmo Marconi Airport, fly

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane plane BLQ - PMO
    5h 51m
  8. Train via Chiusi (Trenitalia)

    1. Take the train from Siena to Chiusi-Chianciano T.train train Re
    2. Take the train from Chiusi-Chianciano T. to Roma Terminitrain train Re
    3. Take the train from Roma Termini to Palermo Centraletrain train Ic
    17h 54m
    €103–247
  9. Drive, car ferry

    1. Drive from Siena to Livornocar car
    2. Take the car ferry from Livorno to Port of Palermocarferry car ferry
    21h 20m
    €58–86

Siena to Palermo by bus

Calendar7Weekly Buses
Duration16hAverage Duration
Ticket€70Cheapest Price
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Questions & Answers

What companies run services between Siena, Italy and Palermo, Italy?

FlixBus operates a bus from Siena to Palermo once daily. Tickets cost €70–130 and the journey takes 16h. Alternatively, you can take a train from Siena to Palermo Centrale via Firenze S.M.N. and Roma Termini in around 16h 24m.

Airlines
Train operators
Bus operators
Ferry operators

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