There are 9 ways to get from Siena to Palermo by bus, plane, train, car, ferry or bus and ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus to Florence, fly to Palermo  •  5 h 3 min

  1. Take the bus from Siena-Via Tozzi to Leopolda
  2. Fly from Florence (FLR) to Palermo (PMO) FLR - PMO

$70 - $199

Cheapest option

Train, train to Pisa, fly to Palermo  •  5 h 28 min

  1. Take the train from Siena to Empoli
  2. Take the train from Empoli to Pisa C.Le
  3. Fly from Pisa (PSA) to Palermo (PMO) PSA - PMO

$44 - $179

7 alternative options

Train, train to Bologna, fly to Palermo  •  6 h 32 min

  1. Take the train from Siena to Firenze Smn
  2. Take the train from Firenze S.Maria Novella to Bologna C.Le
  3. Fly from Bologna (BLQ) to Palermo (PMO) BLQ - PMO

$67 - $240

Bus to Florence, fly to Catania, bus  •  7 h 9 min

  1. Take the bus from Siena-Via Tozzi to Leopolda
  2. Fly from Florence (FLR) to Catania (CTA) FLR - CTA
  3. Take the bus from Catania–Fontanarossa Airport to Palermo

$92 - $231

Train  •  15 h 57 min

  1. Take the train from Siena to Firenze Smn Reg / ...
  2. Take the train from Firenze S.Maria Novella to Roma Termini Fr / ...
  3. Take the train from Roma Termini to Palermo Centrale Ic / ...

$114 - $166

Bus  •  16 h 10 min

  1. Take the bus from SIENA - Pza Stazione FS-Fta SENA to PALERMO - PALERMO-P.Cairoli FS Baltour

$55 - $80

Drive, ferry  •  16 h 28 min

  1. Drive from Siena to Civitavecchia
  2. Take the ferry from Civitavecchia to Palermo

$88 - $150

Train via Chiusi-Chianciano Terme  •  16 h 56 min

  1. Take the train from Siena to Chiusi-Chianciano Terme Reg
  2. Take the train from Chiusi-Chianciano Terme to Roma Termini Rv / ...
  3. Take the train from Roma Termini to Palermo Centrale Ic / ...

$108 - $160

Bus, bus and ferry  •  19 h 13 min

  1. Take the bus from Rinaldo Franci to Firenze Autostazione 131 / ...
  2. Take the bus and ferry from Florence to Palermo Stazione Centrale

$73 - $105

Questions & Answers

The cheapest way to get from Siena to Palermo is to bus which costs 50€ - 70€ and takes 16 h 10 min.

More details

The quickest way to get from Siena to Palermo is to bus and fly which costs 55€ - 170€ and takes 5 h 3 min.

More details

The distance between Siena and Palermo is 601 km.

It takes approximately 5 h 3 min to get from Siena to Palermo, including transfers.

More details

Yes, there is a direct bus departing from SIENA - Pza Stazione FS-Fta SENA and arriving at PALERMO - PALERMO-P.Cairoli FS. Services depart twice daily, and operate every day. The journey takes approximately 16 h 10 min.

More details

No, there is no direct train from Siena to Palermo. However, there are services departing from Siena and arriving at Palermo Centrale via Firenze S.Maria Novella and Roma Termini. The journey, including transfers, takes approximately 15 h 57 min.

More details

What companies run services between Siena, Italy and Palermo, Italy?

You can take a train from Siena to Palermo via Firenze Smn, Firenze S.Maria Novella, and Roma Termini in around 15 h 57 min. Alternatively, Baltour operates a bus from Siena to Palermo twice daily. Tickets cost $55 - $80 and the journey takes 16 h 10 min.

Airlines
Alitalia
Website
alitalia.com
Flights from Florence to Palermo via Rome
Ave. Duration
3 h 6 min
When
Every day
Estimated price
$80 - $280
Flights from Pisa to Palermo via Rome
Ave. Duration
3 h 8 min
When
Every day
Estimated price
$120 - $490
Flights from Bologna to Palermo
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$75 - $330
Flights from Bologna to Palermo via Rome
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$75 - $330
Flights from Florence to Catania via Rome
Ave. Duration
3 h 23 min
When
Every day
Estimated price
$75 - $310
Ryanair
Website
ryanair.com
Flights from Pisa to Palermo
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$30 - $210
Flights from Bologna to Palermo
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$30 - $350
Vueling Airlines
Website
vueling.com
Flights from Florence to Palermo
Ave. Duration
1 h 20 min
When
Wednesday, Friday and Sunday
Estimated price
$85 - $450
Flights from Florence to Catania
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$70 - $410
Train operators
Trenitalia
Phone
+39 06 68475475
Website
trenitalia.com
Train from Siena to Empoli
Ave. Duration
1 h 2 min
Frequency
Hourly
Estimated price
$5 - $12
Website
orario.trenitalia.com
1st Class
$9 - $12
Train from Empoli to Pisa C.Le
Ave. Duration
30 min
Frequency
Every 30 minutes
Estimated price
$3 - $10
Website
orario.trenitalia.com
1st Class
$7 - $10
Train from Siena to Firenze Smn
Ave. Duration
1 h 32 min
Frequency
Hourly
Estimated price
$7 - $16
Website
orario.trenitalia.com
1st Class
$13 - $16
Train from Siena to Chiusi-Chianciano Terme
Ave. Duration
1 h 25 min
Frequency
Hourly
Estimated price
$7 - $16
Website
orario.trenitalia.com
1st Class
$13 - $16
Train from Chiusi-Chianciano Terme to Roma Termini
Ave. Duration
1 h 52 min
Frequency
Every 2 hours
Estimated price
$11 - $25
Website
orario.trenitalia.com
1st Class
$20 - $25
Trenitalia Frecce
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze S.Maria Novella to Bologna C.Le
Ave. Duration
35 min
Frequency
Every 30 minutes
Estimated price
$16 - $23
Website
orario.trenitalia.com
Train from Firenze S.Maria Novella to Roma Termini
Ave. Duration
1 h 32 min
Frequency
Every 30 minutes
Estimated price
$30 - $50
Website
orario.trenitalia.com
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Firenze Santa Maria Novella Station to Bologna Centrale Station
Ave. Duration
38 min
Frequency
Hourly
Estimated price
$18 - $26
Website
italotreno.it
Train from Firenze Santa Maria Novella Station to Roma Termini
Ave. Duration
1 h 32 min
Frequency
Every 3 hours
Estimated price
$27 - $40
Website
italotreno.it
Trenitalia Intercity
Bus operators
Tiemme Spa
Phone
+39.0565.260111
Email
segreteria@tiemmespa.it
Website
tiemmespa.it
Bus from Siena-Via Tozzi to Leopolda
Ave. Duration
1 h 14 min
Frequency
Hourly
Estimated price
$6 - $9
Schedules at
tiemmespa.it
Bus from Rinaldo Franci to Firenze Autostazione
Ave. Duration
1 h 15 min
Frequency
Hourly
Estimated price
$6 - $9
Schedules at
tiemmespa.it
SAIS Autolinee
Baltour
Phone
+39 0861 1991900
Email
info@baltour.it
Website
baltour.it
Bus from SIENA - Pza Stazione FS-Fta SENA to PALERMO - PALERMO-P.Cairoli FS
Ave. Duration
16 h 10 min
Frequency
Twice daily
Estimated price
$55 - $80
Website
http://www.baltour.it/
Autoservizi Salemi Srl
Phone
(+39) 0923 98.11.20
Website
autoservizisalemi.it
Bus and ferry from Florence to Palermo Stazione Centrale
Ave. Duration
16 h 29 min
Frequency
Once daily
Estimated price
$65 - $95
Schedules at
autoservizisalemi.it
Ferry operators

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