The average train between Siena and Mede takes 6h 40m and the fastest train takes 5h 29m. The train service runs several times per day from Siena to Mede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Siena and Mede. The earliest departure is at 7:02 AM in the morning, and the last departure from Siena is at 7:18 PM which arrives into Mede at 5:51 AM. All services require a transfer at Firenze S.M.N. and take an average of 6h 40m. The schedules shown below are for the next available departures.



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Want to know about travelling from Siena to Mede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Mede. However, there are services departing from Siena station and arriving at Mede station via Firenze S.M.N.. The journey, including transfers, takes approximately 6h 40m.
Siena to Mede train services, operated by Trenitalia, depart from Siena station.
Siena to Mede train services, operated by Trenitalia, arrive at Milano Rogoredo station.
Book your Siena to Mede train tickets online with Trenitalia, Trenitalia Frecce and Trenord.
The distance between Siena and Mede is 286.2 km. The road distance is 454 km.
You can take a train from Siena to Mede via Firenze S.M.N., Milan Rogoredo, and Pavia in around 6h 5m.