There are 7 ways to get from Siena to Mede by bus, train, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train via Florence
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the train from Firenze S.M.N. to Milano Rogoredotrain Fr
5h 42m€40–159Bus, train
cheapest- Take the bus from Siena to Piacenzabus Siena
- Take the train from Piacenza to Paviatrain R34
8h 17m€24–41Drive 352.7 km
- Drive from Siena to Medecar 352.7 km
4h 25m€55–80Bus, fly
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Milan Linate Airport (LIN)plane FLR - LIN
8h 33m€133–298Train
- Take the train from Siena to Firenze S.M.N.train Re / ...
- Take the train from Firenze S.M.N. to Milano Rogoredotrain Fr
6h 1m€47–172Bus
- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Genoabus 510 / ...
- Take the bus from Genoa to Alessandriabus
8h 19m€26–45Train via Pisa
- Take the train from Siena to Empolitrain Re
- Take the train from Empoli to Pisa Centraletrain Re
- Take the train from Pisa Centrale to Paviatrain Ic
8h 27m€43–298
Siena to Mede by bus and train
Questions & Answers
The cheapest way to get from Siena to Mede is to bus and train which costs €23 - €45 and takes 8h 17m.
The fastest way to get from Siena to Mede is to drive which takes 4h 25m and costs €55 - €80.
No, there is no direct bus from Siena to Mede. However, there are services departing from Siena and arriving at Mede via Florence Villa Constanza Bus Station, Genoa and Alessandria. The journey, including transfers, takes approximately 8h 19m.
No, there is no direct train from Siena to Mede. However, there are services departing from Siena and arriving at Mede via Firenze S.M.N., Milan Rogoredo and Pavia. The journey, including transfers, takes approximately 6h 1m.
The distance between Siena and Mede is 430 km. The road distance is 352.7 km.
The best way to get from Siena to Mede without a car is to bus and train via Florence which takes 5h 42m and costs €40 - €160.
It takes approximately 5h 42m to get from Siena to Mede, including transfers.
Siena to Mede bus services, operated by FlixBus, depart from Siena station.
Siena to Mede train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Mede is to train which takes 6h 1m and costs €45 - €180. Alternatively, you can bus, which costs €25 - €45 and takes 8h 19m.
What companies run services between Siena, Italy and Mede, Italy?
You can take a train from Siena to Mede via Firenze S.M.N., Milan Rogoredo, and Pavia in around 6h 1m. Alternatively, you can take a bus from Siena to Mede via Florence Villa Constanza Bus Station, Genoa, and Alessandria in around 8h 19m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- €130–280
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- €170–800
Flights from Florence Peretola Airport to Milan Linate Airport via Vienna
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- €100–420
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €200–1,000
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- €170–800
Flights from Florence Peretola Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €130–280
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- €110–1,000
- Website
- austrian.com
Flights from Florence Peretola Airport to Milan Linate Airport via Vienna
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- €100–420
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Saturday
- Estimated price
- €170–800
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- €200–1,000
- Website
- aeroitalia.com
Flights from Florence Peretola Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 5h 40m
- When
- Monday and Friday
- Estimated price
- €100–340
- Website
- flexflight.dk
Flights from Florence Peretola Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 5h 40m
- When
- Monday and Friday
- Estimated price
- €100–340
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Rogoredo
- Ave. Duration
- 1h 44m
- Frequency
- Hourly
- Estimated price
- €40–85
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Pavia
- Ave. Duration
- 3h 8m
- Frequency
- Once daily
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Rogoredo
- Ave. Duration
- 3h 39m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Pavia
- Ave. Duration
- 3h 42m
- Frequency
- 5 times a day
- Estimated price
- €27–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Rogoredo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- €65–120
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €80–120
- 2nd Class
- €65–90
Train from Pisa Centrale to Pavia
- Ave. Duration
- 4h 58m
- Frequency
- 3 times a week
- Estimated price
- €60–110
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €75–110
- 2nd Class
- €60–80
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Milano Rogoredo
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €35–75
- Website
- https://www.italotreno.it/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Piacenza to Pavia
- Ave. Duration
- 1h 16m
- Frequency
- Every 4 hours
- Estimated price
- €5–7
- Website
- https://www.trenord.it/en/
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Pisa Centrale to Pavia
- Ave. Duration
- 4h 58m
- Frequency
- Twice a week
- Estimated price
- €95–270
- Website
- https://www.sbb.ch/en
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena to Piacenza
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- €16–35
- Website
- https://www.itabus.it/en/home
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €4–8
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Genoa
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- €16–27
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Alessandria
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €5–10
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Siena to Mede bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to Mede train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Mede is 353 km. It takes approximately 4h 25m to drive from Siena to Mede.
Book your Siena to Mede train tickets online with Omio.
There are 317+ hotels available in Mede.








































