The average train between Segrate and Iseo takes 2h 20m and the fastest train takes 1h 42m. There is a train service every few hours from Segrate to Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Segrate and Iseo. The earliest departure is at 6:18 AM in the morning, and the last departure from Segrate is at 11:48 PM which arrives into Iseo at 6:24 AM. All services require a transfer at Pioltello Limito and take an average of 2h 20m. The schedules shown below are for the next available departures.


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1h 42m • 2 changes


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2h 8m • 2 changes
Want to know about travelling from Segrate to Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Segrate to Iseo. However, there are services departing from Segrate station and arriving at Iseo station via Brescia. The journey, including transfers, takes approximately 2h 20m.
Segrate to Iseo train services, operated by Trenord, depart from Pioltello Limito station.
Segrate to Iseo train services, operated by Trenord, arrive at Iseo station.
Book your Segrate to Iseo train tickets online with Trenord.
The distance between Segrate and Iseo is 61.5 km. The road distance is 98 km.
You can take a train from Segrate to Iseo via Pioltello Limito and Brescia in around 2h 14m.