The average train between Milan and Iseo takes 1h 57m and the fastest train takes 1h 13m. There is a train service every few hours from Milan to Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Milan and Iseo. The earliest departure is at 7:15 AM in the morning, and the last departure from Milan is at 9:45 PM which arrives into Iseo at 6:28 AM. All services require a transfer, and take on average 1h 57m. The schedules shown below are for the next available departures.

1h 13m • 1 change

1h 13m • 1 change

1h 43m • 1 change

1h 43m • 1 change

1h 13m • 1 change

1h 13m • 1 change

1h 43m • 1 change

1h 43m • 1 change

1h 13m • 1 change

1h 13m • 1 change

1h 43m • 1 change

1h 43m • 1 change

1h 13m • 1 change

1h 13m • 1 change

1h 43m • 1 change

1h 43m • 1 change
Want to know about travelling from Milan to Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Iseo. However, there are services departing from Milan station and arriving at Iseo station via Brescia. The journey, including transfers, takes approximately 1h 57m.
Milan to Iseo train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Iseo train services, operated by Trenitalia Frecce, arrive at Iseo station.
Book your Milan to Iseo train tickets online with Trenitalia Frecce and Trenord.
The distance between Milan and Iseo is 70.5 km. The road distance is 108 km.
You can take a train from Milano Centrale to Iseo via Brescia in around 1h 44m.