The average train between Sion and Iseo takes 7h 48m and the fastest train takes 5h 15m. The train service runs several times per day from Sion to Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Sion and Iseo. The earliest departure is at 7:09 AM in the morning, and the last departure from Sion is at 8:09 PM which arrives into Iseo at 8:24 AM. All services require a transfer at Domodossola and take an average of 7h 48m. The schedules shown below are for the next available departures.



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Want to know about travelling from Sion to Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sion to Iseo. However, there are services departing from Sion station and arriving at Iseo station via Domodossola. The journey, including transfers, takes approximately 7h 48m.
Sion to Iseo train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Sion station.
Sion to Iseo train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Brescia station.
Book your Sion to Iseo train tickets online with Swiss Federal Railways (SBB CFF FFS), Trenord and Trenitalia Frecce.
The distance between Sion and Iseo is 217.8 km. The road distance is 319 km.
You can take a train from Sion to Iseo via Domodossola, Milano Centrale, and Brescia in around 5h 55m.