There are 8 ways to get from Prague to Brussels by plane, subway, train, bus, night train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Brussels  •  4 h 14 min

  1. Fly from Prague (PRG) to Brussels (BRU) PRG - BRU

$41 - $203

Cheapest option

Bus  •  14 h 5 min

  1. Take the bus from Prague, Prague ÚAN Florenc to Brussels, Brussels-North station N84 / ...

$30 - $90

6 alternative options

Subway, fly to Charleroi  •  5 h 17 min

  1. Take the subway from Staroměstská to Nádraží Veleslavín
  2. Fly from Prague (PRG) to Charleroi (CRL) PRG - CRL

$39 - $162

Fly to Amsterdam, train  •  6 h 7 min

  1. Fly from Prague (PRG) to Amsterdam (AMS) PRG - AMS
  2. Take the train from Schiphol Airport to Brussel-Zuid/Midi

$107 - $292

Train  •  10 h 19 min

  1. Take the train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
  2. Take the train from Nürnberg Hbf to Köln Messe/Deutz Gl.11-12 Ice
  3. Take the train from Köln Hauptbahnhof to Brusel Nord Ice

$169 - $258

Bus via Leuven  •  15 h 49 min

  1. Take the bus from Prague, Prague ÚAN Florenc to Leuven N84

$58 - $95

Night train, train  •  12 h 20 min

  1. Take the night train from Praha hl.n. (Autobusová St. Wilsonova) to Frankfurt(M)Hbf Stuttgarter Str.
  2. Take the train from Frankfurt(Main)Hbf to Köln Hbf Ice / ...
  3. Take the train from Köln Hauptbahnhof to Brusel Nord Ice

$177 - $260

Drive  •  8 h 10 min

  1. Drive from Prague to Brussels 561.5 miles

$110 - $170

Questions & Answers

Yes, there is a direct bus departing from Prague, Prague ÚAN Florenc and arriving at Brussels, Brussels-North station station. Services depart three times a day, and operate every day. The journey takes approximately 14 h 5 min.

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No, there is no direct train from Prague to Brussels. However, there are services departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Brusel Nord via Nürnberg Hbf, Köln, Deutz Bf Deutz / Messe LANXESS arena and Köln Hauptbahnhof. The journey, including transfers, takes approximately 10 h 19 min.

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The distance between Prague and Brussels is 717 km. The road distance is 898.3 km.

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The best way to get from Prague to Brussels without a car is to train which takes 10 h 19 min and costs .

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It takes approximately 4 h 14 min to get from Prague to Brussels, including transfers.

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Prague to Brussels bus services, operated by FlixBus, depart from Prague, Prague ÚAN Florenc station.

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Prague to Brussels train services, operated by Czech Railways (ČD), depart from Praha hl.n. (Autobusová St. Wilsonova) station.

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The best way to get from Prague to Brussels is to fly which takes 4 h 14 min and costs . Alternatively, you can train, which costs and takes 10 h 19 min, you could also bus, which costs and takes 14 h 5 min.

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The quickest flight from Prague Airport to Brussels Airport is the direct flight which takes 1 h 25 min.

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Prague to Brussels bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

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Map of how to get from Prague to Brussels.
Launch map view
  • Distance: 448.3 miles
  • Duration: 4 h 14 min

What companies run services between Prague, Czech Republic and Brussels, Belgium?

Brussels Airlines, CSA and four other airlines fly from Prague to Brussels every 2 hours. Alternatively, you can take a train from Prague to Brussels via Nürnberg ZOB, Nürnberg Hbf, Köln Messe/Deutz Gl.11-12, Köln, Deutz Bf Deutz / Messe LANXESS arena, Köln, Dom / Hbf, and Köln Hauptbahnhof in around 10 h 19 min.

Airlines
CSA
Website
csa.cz
Flights from Prague to Brussels
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$35 - $310
Flights from Prague to Amsterdam
Ave. Duration
1 h 36 min
When
Every day
Estimated price
$100 - $440
Lufthansa
Website
lufthansa.com
Flights from Prague to Brussels via Frankfurt
Ave. Duration
3 h 25 min
When
Every day
Estimated price
$160 - $850
Flights from Prague to Brussels via Munich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$160 - $850
Flights from Prague to Amsterdam via Frankfurt
Ave. Duration
3 h 25 min
When
Every day
Estimated price
$180 - $800
KLM
Website
klm.com
Flights from Prague to Brussels via Amsterdam
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$150 - $600
Flights from Prague to Amsterdam
Ave. Duration
1 h 36 min
When
Every day
Estimated price
$120 - $470
Brussels Airlines
Website
brusselsairlines.com
Flights from Prague to Brussels
Ave. Duration
1 h 28 min
When
Every day
Estimated price
$50 - $390
Scandinavian Airlines
Website
flysas.com
Flights from Prague to Brussels via Copenhagen
Ave. Duration
3 h 47 min
When
Monday, Thursday and Sunday
Estimated price
$120 - $600
Flights from Prague to Amsterdam via Copenhagen
Ave. Duration
3 h 50 min
When
Monday and Thursday
Estimated price
$110 - $600
easyJet
Website
easyjet.com
Flights from Prague to Amsterdam
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$55 - $280
Swiss
Website
swiss.com
Flights from Prague to Brussels via Zurich
Ave. Duration
3 h 35 min
When
Monday to Saturday
Estimated price
$160 - $850
Ryanair
Website
ryanair.com
Flights from Prague to Charleroi
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$21 - $200
Eurowings
Website
eurowings.com
Flights from Prague to Amsterdam via Hamburg
Ave. Duration
3 h 5 min
When
Friday and Sunday
Estimated price
$120 - $600
Austrian Airlines
Website
austrian.com
Flights from Prague to Amsterdam via Vienna
Ave. Duration
3 h 55 min
When
Monday to Friday
Estimated price
$190 - $850
Air France
Website
airfrance.com
Flights from Prague to Amsterdam via Paris CDG
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$160 - $600
Train operators
Prague Public Transit Co.
Thalys
Website
thalys.com
Train from Schiphol Airport to Brussel-Zuid/Midi
Ave. Duration
1 h 34 min
Frequency
Hourly
Estimated price
$55 - $80
Website
thalys.com
2nd Class
$55 - $80
1st Class
$80 - $110
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
cd.cz
Night train from Praha hl.n. (Autobusová St. Wilsonova) to Frankfurt(M)Hbf Stuttgarter Str.
Ave. Duration
7 h 35 min
Frequency
Once daily
Estimated price
$90 - $130
Website
cd.cz
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Nürnberg Hbf to Köln Messe/Deutz Gl.11-12
Ave. Duration
3 h 14 min
Frequency
Hourly
Estimated price
$80 - $120
Website
bahn.de
Train from Köln Hauptbahnhof to Brusel Nord
Ave. Duration
1 h 43 min
Frequency
Every 4 hours
Estimated price
$45 - $70
Website
bahn.de
Train from Frankfurt(Main)Hbf to Köln Hbf
Ave. Duration
1 h 23 min
Frequency
Hourly
Estimated price
$40 - $60
Website
bahn.de
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Prague, Prague ÚAN Florenc to Brussels, Brussels-North station
Ave. Duration
14 h 5 min
Frequency
Twice daily
Estimated price
$50 - $90
Website
flixbus.co.uk
Bus from Prague, Prague ÚAN Florenc to Leuven
Ave. Duration
15 h
Frequency
6 times a week
Estimated price
$50 - $90
Website
flixbus.co.uk
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Prague, ÚAN Florenc to Brussels, CCN, gare du Nord
Ave. Duration
12 h
Frequency
Twice daily
Estimated price
$30 - $40
Website
regiojet.com
Eurolines CZ
Email
info@eurolines.cz
Website
elines.cz
Bus from Praha ÚAN Florenc to Brussels
Ave. Duration
13 h 30 min
Frequency
6 times a week
Estimated price
$50 - $90
Schedules at
elines.cz

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More Questions & Answers

Prague to Brussels train services, operated by Deutsche Bahn, arrive at Brusel Nord station.

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Yes, the driving distance between Prague to Brussels is 898 km. It takes approximately 8 h 10 min to drive from Prague to Brussels.

Get driving directions

CSA, KLM, Brussels Airlines and three other airlines offer flights from Prague Airport to Brussels Airport.

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Book your Prague to Brussels bus tickets online with FlixBus and Distribusion.

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There are 951+ hotels available in Brussels. Prices start at $69 USD per night.

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