The average train between Potsdam and Mainz takes 5h 49m and the fastest train takes 5h 12m. There is a train service every few hours from Potsdam to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Potsdam and Mainz. The earliest departure is at 3:44 AM at night, and the last departure from Potsdam is at 11:32 PM which arrives into Mainz at 6:23 AM. All services require a transfer at Berlin Hbf and take an average of 5h 49m. The schedules shown below are for the next available departures.


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5h 20m • 2 changesWant to know about travelling from Potsdam to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Potsdam to Mainz. However, there are services departing from Berlin Hbf station and arriving at Frankfurt station via Frankfurt station. The journey, including transfers, takes approximately 5h 49m.
Potsdam to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Berlin Hbf station.
Potsdam to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
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The distance between Potsdam and Mainz is 428 km. The road distance is 518 km.
Deutsche Bahn Intercity (DB IC) operates a train from Berlin Hbf to Frankfurt hourly. Tickets cost €85–200 and the journey takes 4h 1m.