The average train between Potsdam and Mainz takes 7h 4m and the fastest train takes 6h 10m. There is a train service every few hours from Potsdam to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Potsdam and Mainz. The earliest departure is at 4:41 AM at night, and the last departure from Potsdam is at 10:41 PM which arrives into Mainz at 6:22 AM. All services require a transfer at Berlin Hbf and take an average of 7h 4m. The schedules shown below are for the next available departures.


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Want to know about travelling from Potsdam to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Potsdam to Mainz. However, there are services departing from Potsdam station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 7h 4m.
Potsdam to Mainz train services, operated by S-Bahn Berlin, depart from Berlin Hbf station.
Potsdam to Mainz train services, operated by S-Bahn Berlin, arrive at Frankfurt station.
Book your Potsdam to Mainz train tickets online with S-Bahn Berlin, Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Potsdam and Mainz is 428 km. The road distance is 576 km.
Deutsche Bahn Intercity (DB IC) operates a train from Berlin Hbf to Frankfurt hourly. Tickets cost €95–340 and the journey takes 4h 1m.