The average train between Pisa and Prague takes 20h 39m and the fastest train takes 16h 44m. The train service runs several times per day from Pisa to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pisa and Prague. The earliest departure is at 6:54 AM in the morning, and the last departure from Pisa is at 6:01 PM which arrives into Prague at 3:39 PM. All services require a transfer at Firenze S.M.N. and take an average of 20h 39m. The schedules shown below are for the next available departures.





16h 44m • 5 changes
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23h 30m • 5 changes
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25h 45m • 5 changes





16h 48m • 5 changes
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23h 45m • 5 changes
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21h 38m • 5 changes





16h 44m • 5 changes
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23h 30m • 5 changes
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21h 38m • 5 changes





16h 44m • 5 changes
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23h 30m • 5 changes
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21h 38m • 5 changes
Want to know about travelling from Pisa to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Prague. However, there are services departing from Pisa station and arriving at Prague station via Firenze S.M.N.. The journey, including transfers, takes approximately 20h 39m.
Pisa to Prague train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Prague train services, operated by Trenitalia, arrive at Praha Hlavni Nadrazi station.
Book your Pisa to Prague train tickets online with Trenitalia, Trenitalia Frecce and 4 other operators.
The distance between Pisa and Prague is 772 km. The road distance is 1,157 km.
You can take a train from Pisa Centrale to Praha Hlavni Nadrazi via Firenze S.M.N., Bolzano Bozen, Brennero - Brenner, Innsbruck Hauptbahnhof, and Linz Hbf in around 15h 58m.