The average train between Pisa and Manfredonia takes 13h 57m and the fastest train takes 9h 13m. The train service runs several times per day from Pisa to Manfredonia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pisa and Manfredonia. The earliest departure is at 5:37 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Manfredonia at 1:34 PM. All services require a transfer at Roma Termini and take an average of 13h 57m. The schedules shown below are for the next available departures.


9h 21m • 2 changes
Arrives next day


15h 47m • 2 changes
Arrives next day


17h 51m • 2 changes


9h 21m • 2 changes
Arrives next day


15h 47m • 2 changes
Arrives next day


17h 51m • 2 changes


9h 21m • 2 changes
Arrives next day


15h 47m • 2 changes
Arrives next day


16h 56m • 2 changes


11h 23m • 2 changes
Arrives next day


16h 31m • 2 changes
Arrives next day


16h 56m • 2 changes
Want to know about travelling from Pisa to Manfredonia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Manfredonia. However, there are services departing from Pisa station and arriving at Manfredonia station via Roma Termini. The journey, including transfers, takes approximately 13h 57m.
Pisa to Manfredonia train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Manfredonia train services, operated by Trenitalia, arrive at Foggia station.
Book your Pisa to Manfredonia train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Pisa and Manfredonia is 506.5 km. The road distance is 722 km.
You can take a train from Pisa Centrale to Manfredonia via Roma Termini and Foggia in around 7h 50m.