The average train between Nyon and Milan takes 5h 23m and the fastest train takes 4h 25m. The train service runs several times per day from Nyon to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Nyon and Milan. The earliest departure is at 5:24 AM in the morning, and the last departure from Nyon is at 6:25 PM which arrives into Milan at 10:50 PM. All services require a transfer at Lausanne and take an average of 5h 23m. The schedules shown below are for the next available departures.


4h 26m • 2 changes


9h 46m • 2 changes


4h 25m • 2 changes


4h 25m • 2 changes


4h 26m • 2 changes


9h 46m • 2 changes


4h 25m • 2 changes


4h 25m • 2 changes


4h 26m • 2 changes


9h 46m • 2 changes


4h 25m • 2 changes


4h 25m • 2 changes


4h 26m • 2 changes


9h 46m • 2 changes


4h 25m • 2 changes


4h 25m • 2 changes
Want to know about travelling from Nyon to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Nyon to Milan. However, there are services departing from Nyon station and arriving at Milan station via Domodossola. The journey, including transfers, takes approximately 5h 23m.
Nyon to Milan train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Lausanne station.
Nyon to Milan train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Book your Nyon to Milan train tickets online with Swiss Federal Railways (SBB CFF FFS) and Trenitalia EuroCity.
The distance between Nyon and Milan is 250 km. The road distance is 342 km.
You can take a train from Nyon to Milano Centrale via Lausanne and Domodossola in around 6h 7m.