Mainz to Milan trains

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Trip Overview

The average train between Mainz and Milan takes 9h 50m and the fastest train takes 7h 31m. The train service runs several times per day from Mainz to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 50m
Duration: 652 km
Distance: €195
Average price: Every 4 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain

9h 14m

€83–343

Mainz to Milan train times

Trains run every 4 hours between Mainz and Milan. The earliest departure is at 1:43 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Milan at 11:17 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 9h 50m. The schedules shown below are for the next available departures.

Departing Tuesday, October 27, 2026

9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
1:13 PM → 9:17 PM
8h 4m • 3 changes
4:42 PM → 7:17 AM
Arrives next day
14h 35m • 3 changes
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Departing Wednesday, October 28, 2026

1:43 AM → 1:17 PM
11h 34m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Departing Thursday, October 29, 2026

1:43 AM → 1:17 PM
11h 34m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Departing Friday, October 30, 2026

2:01 AM → 1:17 PM
11h 16m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Departing Saturday, October 31, 2026

5:40 AM → 1:17 PM
7h 37m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
1:13 PM → 9:17 PM
8h 4m • 3 changes
Show more

Departing Sunday, November 1, 2026

5:40 AM → 1:17 PM
7h 37m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
1:13 PM → 9:17 PM
8h 4m • 3 changes
Show more

Departing Monday, November 2, 2026

5:40 AM → 1:17 PM
7h 37m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Mainz to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.