The average train between Ortona and Milan takes 6h 26m and the fastest train takes 4h 54m. The train service runs several times per day from Ortona to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Ortona and Milan. The earliest departure is at 7:26 AM in the morning, and the last departure from Ortona is at 9:33 PM which arrives into Milan at 9:35 AM. All services require a transfer, and take on average 6h 26m. The schedules shown below are for the next available departures.

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Want to know about travelling from Ortona to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Ortona to Milan. However, there are services departing from Ortona station and arriving at Milan station via Milano Centrale. The journey, including transfers, takes approximately 6h 26m.
Ortona to Milan train services, operated by Trenitalia, depart from Pescara Centrale station.
Ortona to Milan train services, operated by Trenitalia, arrive at Milano Centrale station.
Book your Ortona to Milan train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Ortona and Milan is 542.4 km. The road distance is 584 km.
Trenitalia Frecce operates a train from Pescara Centrale to Milano Centrale every 3 hours. Tickets cost €80–160 and the journey takes 5h. Trenitalia Intercity also services this route 5 times a day.