The average train between Neu-Isenburg and Cologne takes 1h 28m and the fastest train takes 1h 24m. There is a train service every few hours from Neu-Isenburg to Cologne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Neu-Isenburg and Cologne. The earliest departure is at 5:20 AM in the morning, and the last departure from Neu-Isenburg is at 8:50 PM which arrives into Cologne at 10:14 PM. All services require a transfer at Frankfurt and take an average of 1h 28m. The schedules shown below are for the next available departures.

1h 54m • 1 change

1h 24m • 1 change

1h 24m • 1 change

1h 24m • 1 change

1h 54m • 1 change

1h 24m • 1 change

1h 24m • 1 change

1h 24m • 1 change

1h 54m • 1 change

1h 24m • 1 change

1h 24m • 1 change

1h 24m • 1 change

1h 54m • 1 change

1h 24m • 1 change

1h 24m • 1 change

1h 24m • 1 change
Want to know about travelling from Neu-Isenburg to Cologne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Neu-Isenburg to Cologne. However, there are services departing from Neu-Isenburg station and arriving at Cologne station via Köln Messe/Deutz Bf. The journey, including transfers, takes approximately 1h 28m.
Neu-Isenburg to Cologne train services, operated by Verkehrsgesellschaft Frankfurt (VGF-FFM), depart from Frankfurt station.
Neu-Isenburg to Cologne train services, operated by Verkehrsgesellschaft Frankfurt (VGF-FFM), arrive at Köln Messe/Deutz Bf station.
The distance between Neu-Isenburg and Cologne is 157.8 km. The road distance is 185 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Köln Messe/Deutz Bf hourly. Tickets cost €35–80 and the journey takes 1h 6m.