Train Mendrisio to Genoa from €54 | Tickets & Timetables

Trip Overview

The average train between Mendrisio and Genoa takes 4h 5m and the fastest train takes 2h 45m. The train service runs several times per day from Mendrisio to Genoa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 5m
Duration: 263 km
Distance: €54
Average price: Every 2 hours
Frequency

Train via Milan

best

Take the train from Mendrisio to Milano Centraletrain Re80
Take the train from Milano Centrale to Genova Brignoletrain Ic

4h 53m

€41–118

Mendrisio to Genoa train times

Trains run every 2 hours between Mendrisio and Genoa. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 9:18 PM which arrives into Genoa at 7:53 AM. All services require a transfer, and take on average 4h 5m. The schedules shown below are for the next available departures.

Departing Wednesday, April 29, 2026

4:18 PM → 7:52 PM
3h 34m • 1 change
5:18 PM → 8:03 PM
2h 45m • 1 change
7:18 PM → 10:49 PM
3h 31m • 1 change
8:18 PM → 12:05 AM
Arrives next day
3h 47m • 1 change
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Departing Thursday, April 30, 2026

6:18 AM → 9:53 AM
3h 35m • 1 change
10:18 AM → 1:53 PM
3h 35m • 1 change
11:18 AM → 2:27 PM
3h 9m • 1 change
12:18 PM → 3:53 PM
3h 35m • 1 change
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Departing Friday, May 1, 2026

6:18 AM → 9:53 AM
3h 35m • 1 change
7:18 AM → 10:27 AM
3h 9m • 1 change
10:18 AM → 1:53 PM
3h 35m • 1 change
11:18 AM → 2:27 PM
3h 9m • 1 change
Show more

Departing Saturday, May 2, 2026

6:18 AM → 9:53 AM
3h 35m • 1 change
10:18 AM → 1:53 PM
3h 35m • 1 change
11:18 AM → 2:27 PM
3h 9m • 1 change
12:18 PM → 3:53 PM
3h 35m • 1 change
Show more

Departing Sunday, May 3, 2026

6:18 AM → 9:53 AM
3h 35m • 1 change
7:18 AM → 10:27 AM
3h 9m • 1 change
10:18 AM → 1:53 PM
3h 35m • 1 change
11:18 AM → 2:27 PM
3h 9m • 1 change
Show more

Departing Monday, May 4, 2026

6:18 AM → 9:53 AM
3h 35m • 1 change
10:18 AM → 1:53 PM
3h 35m • 1 change

Frequently asked questions

Want to know about travelling from Mendrisio to Genoa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.