The average train between Mayen and Prague takes 12h 23m and the fastest train takes 10h 25m. The train service runs several times per day from Mayen to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Mayen and Prague. The earliest departure is at 5:16 AM in the morning, and the last departure from Mayen is at 10:16 PM which arrives into Prague at 4:21 PM. All services require a transfer at Andernach and take an average of 12h 23m. The schedules shown below are for the next available departures.




10h 25m • 4 changes




10h 25m • 4 changes




10h 26m • 4 changes
Arrives next day




15h 5m • 4 changes




11h 5m • 4 changes




10h 25m • 4 changes




10h 25m • 4 changes




10h 26m • 4 changes




11h 5m • 4 changes




10h 25m • 4 changes




10h 25m • 4 changes




10h 26m • 4 changes




11h 5m • 4 changes




10h 25m • 4 changes




10h 25m • 4 changes




10h 26m • 4 changes




10h 25m • 4 changes




10h 25m • 4 changes




10h 26m • 4 changes
Arrives next day




20h 47m • 4 changes




11h 5m • 4 changes




10h 25m • 4 changes




10h 25m • 4 changes




10h 26m • 4 changes
Want to know about travelling from Mayen to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mayen to Prague. However, there are services departing from Mayen station and arriving at Prague station via Nürnberg Hbf. The journey, including transfers, takes approximately 12h 23m.
Mayen to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Koblenz Hauptbahnhof station.
Mayen to Prague train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Praha Hlavni Nadrazi station.
Book your Mayen to Prague train tickets online with Deutsche Bahn Regio (DB Regional), National Express and 3 other operators.
The distance between Mayen and Prague is 512.7 km. The road distance is 735 km.
You can take a train from Mayen Ostbahnhof to Praha Hlavni Nadrazi via Andernach, Koblenz Hbf, Koblenz Hauptbahnhof, Nürnberg Hbf, and Schwandorf in around 11h 39m.