The average train between Mainz and Southampton takes 9h 14m and the fastest train takes 7h 34m. The train service runs several times per day from Mainz to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Southampton. The earliest departure is at 6:14 AM in the morning, and the last departure from Mainz is at 7:35 PM which arrives into Southampton at 10:48 AM. All services require a transfer at Frankfurt and take an average of 9h 14m. The schedules shown below are for the next available departures.




8h 38m • 4 changes



7h 35m • 4 changes



8h 35m • 4 changes



8h 35m • 4 changes



8h 46m • 4 changes



7h 46m • 4 changes



8h 46m • 4 changes



7h 46m • 4 changes



8h 35m • 4 changes



8h 34m • 4 changes



8h 37m • 4 changes



7h 35m • 4 changes



8h 35m • 4 changes



8h 34m • 4 changes



8h 37m • 4 changes



7h 35m • 4 changes



8h 35m • 4 changes



8h 34m • 4 changes



8h 37m • 4 changes



7h 35m • 4 changes



8h 35m • 4 changes



8h 34m • 4 changes



8h 37m • 4 changes



7h 35m • 4 changesWant to know about travelling from Mainz to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Southampton. However, there are services departing from Mainz station and arriving at Southampton station via Bruxelles Midi. The journey, including transfers, takes approximately 9h 14m.
Mainz to Southampton train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Southampton train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Southampton Central station.
Book your Mainz to Southampton train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 5 other operators.
The distance between Mainz and Southampton is 692.8 km. The road distance is 916 km.
You can take a train from Mainz, Römisches Theater to Southampton Central via Frankfurt, Bruxelles Midi, Brussel-Zuid / Bruxelles-Midi, London St Pancras Intl, Euston station, Waterloo Station, and London Waterloo in around 8h 53m.