Mainz to Perugia trains

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Trip Overview

The average train between Mainz and Perugia takes 16h 30m and the fastest train takes 12h 35m. The train service runs several times per day from Mainz to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 30m
Duration: 1,107 km
Distance: €251
Average price: Every 4 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Firenze S.M.N.train Fr
Take the train from Firenze S.M.N. to Perugiatrain

14h 28m

€127–409

Mainz to Perugia train times

Trains run every 4 hours between Mainz and Perugia. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Perugia at 4:21 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 16h 30m. The schedules shown below are for the next available departures.

Departing Tuesday, October 20, 2026

9:13 AM → 10:20 PM
13h 7m • 5 changes
1:13 PM → 10:17 AM
Arrives next day
21h 4m • 5 changes
4:53 PM → 2:25 PM
Arrives next day
21h 32m • 5 changes
11:08 PM → 4:21 PM
Arrives next day
17h 13m • 5 changes

Departing Wednesday, October 21, 2026

5:40 AM → 6:26 PM
12h 46m • 5 changes
7:46 AM → 8:21 PM
12h 35m • 5 changes
9:13 AM → 10:20 PM
13h 7m • 5 changes
1:13 PM → 10:17 AM
Arrives next day
21h 4m • 5 changes
Show more

Departing Thursday, October 22, 2026

5:40 AM → 6:26 PM
12h 46m • 5 changes
7:46 AM → 8:21 PM
12h 35m • 5 changes
9:13 AM → 10:20 PM
13h 7m • 5 changes
1:13 PM → 10:17 AM
Arrives next day
21h 4m • 5 changes
Show more

Departing Friday, October 23, 2026

5:40 AM → 6:26 PM
12h 46m • 5 changes
7:46 AM → 8:21 PM
12h 35m • 5 changes
9:13 AM → 10:20 PM
13h 7m • 5 changes
1:13 PM → 10:17 AM
Arrives next day
21h 4m • 5 changes
Show more

Departing Saturday, October 24, 2026

1:38 AM → 4:21 PM
14h 43m • 5 changes
1:43 AM → 6:26 PM
16h 43m • 5 changes
6:22 AM → 8:21 PM
13h 59m • 5 changes
9:13 AM → 10:19 PM
13h 6m • 5 changes
Show more

Departing Sunday, October 25, 2026

2:38 AM → 4:21 PM
14h 43m • 5 changes
6:22 AM → 8:23 PM
14h 1m • 5 changes
9:13 AM → 10:20 PM
13h 7m • 5 changes
1:13 PM → 10:17 AM
Arrives next day
21h 4m • 5 changes
Show more

Departing Monday, October 26, 2026

1:43 AM → 6:26 PM
16h 43m • 5 changes
7:46 AM → 8:21 PM
12h 35m • 5 changes
9:13 AM → 10:20 PM
13h 7m • 5 changes

Frequently asked questions

Want to know about travelling from Mainz to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Perugia.

Launch map view

Distance: 1,106.6 km
Duration: 16h 30m

What companies run services between Mainz, Germany and Perugia, Italy?

You can take a train from Mainz, Hauptbahnhof to Perugia via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 14h 28m.

Operators