There are 11 ways to get from Mainz to Perugia by plane, train, train (Trenitalia), bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Perugiatrain
7h 21m€144–329Fly to Fiumicino International Airport, train
cheapest- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
- Take the train from Roma Termini to Folignotrain
7h 57m€80–203Train
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Perugiatrain
14h 23m€129–730Bus via Florence
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence to Perugiabus FlixBus N504
19h 24mTrain, night train
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain 11 / ...
- Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain Nj
- Take the train from Verona Porta Nuova to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Perugiatrain
21h 5m€116–346Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Perugiatrain
7h 46m€127–324Fly to Pisa International Airport, train
- Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane FRA - PSA
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Perugiatrain
8h 33m€136–310Fly to Venice Marco Polo Airport, train
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Perugiatrain
9h 25m€123–329Fly to Milan Linate Airport, train
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
- Take the train from Milano P.Garibaldi to Perugiatrain
8h 39m€108–277Bus
- Take the bus from Frankfurt central train station to Riminibus N422
- Take the bus from Rimini to Perugiabus N433
21h 9m€106–182Drive 1,111.3 km
- Drive from Mainz to Perugiacar 1,111.3 km
10h 28m€173–250
Mainz to Perugia by train
Questions & Answers
The cheapest way to get from Mainz to Perugia is to fly and train which costs €80 - €210 and takes 7h 57m.
The fastest way to get from Mainz to Perugia is to fly and train which takes 7h 21m and costs €140 - €330.
No, there is no direct bus from Mainz to Perugia. However, there are services departing from Mainz, Brückenplatz and arriving at Perugia via Wiesbaden Gartenfeldstraße P+R and Florence. The journey, including transfers, takes approximately 19h 24m.
No, there is no direct train from Mainz to Perugia. However, there are services departing from Mainz, Hauptbahnhof and arriving at Perugia via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 14h 23m.
The distance between Mainz and Perugia is 905 km. The road distance is 1111.3 km.
The best way to get from Mainz to Perugia without a car is to train which takes 14h 23m and costs €120 - €750.
It takes approximately 7h 21m to get from Mainz to Perugia, including transfers.
Mainz to Perugia bus services, operated by Onebus, depart from Wiesbaden Gartenfeldstraße P+R station.
Mainz to Perugia train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Perugia is to train which takes 14h 23m and costs €120 - €750. Alternatively, you can bus via Florence, which costs and takes 19h 24m.
What companies run services between Mainz, Germany and Perugia, Italy?
You can take a train from Mainz, Hauptbahnhof to Perugia via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 14h 23m. Alternatively, you can take a bus from Mainz, Brückenplatz to Perugia via Wiesbaden Hauptbahnhof, Wiesbaden Gartenfeldstraße P+R, and Florence in around 19h 24m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €130–600
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €170–650
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €70–120
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- €70–120
Flights from Frankfurt to Fiumicino International Airport via Milan Linate Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–490
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €140–500
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €150–550
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–310
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €130–470
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–490
Flights from Frankfurt to Milan Linate Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €50–340
- Website
- ita-airways.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €130–600
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €70–120
Flights from Frankfurt to Fiumicino International Airport via Milan Linate Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–490
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €140–500
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–310
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–470
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–490
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €170–600
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €140–490
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €150–550
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–490
- Website
- condor.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €65–130
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €65–170
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- €100–360
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h 5m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €90–300
Flights from Frankfurt to Venice Marco Polo Airport via Zurich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €85–290
- Website
- easyjet.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €45–120
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €35–130
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- €9–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–70
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 59m
- Frequency
- Every 4 hours
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €10–21
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €16–35
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- €22–45
- Schedules at
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–90
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- €22–45
- Schedules at
- Trenitalia Frecce
Train from Verona Porta Nuova to Firenze S.M.N.
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €30–60
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- €22–45
- Schedules at
- Trenitalia Frecce
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 42m
- Frequency
- 3 times a day
- Estimated price
- €21–45
- Schedules at
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- €22–45
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- €22–45
- Schedules at
- Trenitalia Frecce
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €35–70
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Perugia
- Ave. Duration
- 1h 31m
- Frequency
- Twice daily
- Estimated price
- €22–45
- Schedules at
- Trenitalia Frecce
Train from Milano P.Garibaldi to Perugia
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €65–130
- Schedules at
- Trenitalia Frecce
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €12–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €45–200
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €19–85
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- €14–20
- Schedules at
- Süwex
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- €17–27
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €16–26
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €28–60
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 47 min
- Frequency
- 4 times a day
- Estimated price
- €11–25
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €85–260
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €27–80
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 41m
- Frequency
- 4 times a day
- Estimated price
- €40–80
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 24 min
- Frequency
- 5 times a day
- Estimated price
- €12–23
- Website
- Italo Treno
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €30–65
- Website
- Italo Treno
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Stuttgart Hbf to Verona Porta Nuova
- Ave. Duration
- 12h 32m
- Frequency
- Twice daily
- Estimated price
- €45–130
- Website
- Nightjet
- Sleeper Carriage
- €100–130
- Couchette Carriage
- €75–90
- Seating Carriage
- €45–60
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 5m
- Frequency
- Once a week
- Website
- Onebus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Florence to Perugia
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- €11–19
- Website
- Flixbus
Bus from Frankfurt central train station to Rimini
- Ave. Duration
- 14h 45m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- Flixbus
Bus from Rimini to Perugia
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- €17–28
- Website
- Flixbus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
More Questions & Answers
Mainz to Perugia bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Mainz to Perugia train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Perugia is 1111 km. It takes approximately 10h 28m to drive from Mainz to Perugia.
Book your Mainz to Perugia train tickets online with Omio.
Book your Mainz to Perugia bus tickets online with Omio.
There are 2179+ hotels available in Perugia.

















































