The average train between Mainz and Paderborn takes 5h 8m and the fastest train takes 4h 6m. There is a train service every few hours from Mainz to Paderborn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Paderborn. The earliest departure is at 2:35 AM at night, and the last departure from Mainz is at 10:32 PM which arrives into Paderborn at 7:10 AM. All services require a transfer at Frankfurt and take an average of 5h 8m. The schedules shown below are for the next available departures.


5h 35m • 2 changes


4h 35m • 2 changes


5h 3m • 2 changes


4h 35m • 2 changes


4h 36m • 2 changes


4h 59m • 2 changes


4h 36m • 2 changes


4h 41m • 2 changes


6h 6m • 2 changes


4h 59m • 2 changes


4h 36m • 2 changes


4h 41m • 2 changes
Want to know about travelling from Mainz to Paderborn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Paderborn. However, there are services departing from Mainz station and arriving at Paderborn station via Frankfurt. The journey, including transfers, takes approximately 5h 8m.
Mainz to Paderborn train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Paderborn train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Paderborn Hbf station.
Book your Mainz to Paderborn train tickets online with Deutsche Bahn Regio (DB Regional), National Express and 3 other operators.
The distance between Mainz and Paderborn is 195.8 km. The road distance is 334 km.
You can take a train from Mainz, Römisches Theater to Paderborn Hbf via Frankfurt and Kassel-Wilhelmshoehe in around 3h 44m.