The average train between Mainz and Paderborn takes 4h 51m and the fastest train takes 4h 1m. There is a train service every few hours from Mainz to Paderborn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Paderborn. The earliest departure is at 3:34 AM at night, and the last departure from Mainz is at 7:35 PM which arrives into Paderborn at 7:10 AM. All services require a transfer at Frankfurt and take an average of 4h 51m. The schedules shown below are for the next available departures.


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4h 36m • 2 changesWant to know about travelling from Mainz to Paderborn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Paderborn. However, there are services departing from Mainz, Römisches Theater station and arriving at Paderborn Hbf station via Frankfurt station and Kassel Bahnhof Wilhelmshöhe station. The journey, including transfers, takes approximately 4h 51m.
Mainz to Paderborn train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Paderborn train services, operated by National Express, arrive at Paderborn Hbf station.
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The distance between Mainz and Paderborn is 195.8 km. The road distance is 250 km.
You can take a train from Mainz, Römisches Theater to Paderborn Hbf via Frankfurt and Kassel-Wilhelmshoehe in around 4h 15m.