The average train between Mainz and Paderborn takes 4h 36m and the fastest train takes 3h 54m. The train service runs several times per day from Mainz to Paderborn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Mainz and Paderborn. The earliest departure is at 3:34 AM at night, and the last departure from Mainz is at 8:34 PM which arrives into Paderborn at 7:10 AM. All services require a transfer at Frankfurt and take an average of 4h 36m. The schedules shown below are for the next available departures.


4h 36m • 2 changes


4h 36m • 2 changes


3h 54m • 2 changes


4h 33m • 2 changes


4h 36m • 2 changes


4h 36m • 2 changes


3h 54m • 2 changes


4h 33m • 2 changes


4h 36m • 2 changes


4h 36m • 2 changes


3h 54m • 2 changes


4h 33m • 2 changes
Want to know about travelling from Mainz to Paderborn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Paderborn. However, there are services departing from Mainz station and arriving at Paderborn station via Frankfurt. The journey, including transfers, takes approximately 4h 36m.
Mainz to Paderborn train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Paderborn train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Paderborn Hbf station.
Book your Mainz to Paderborn train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Paderborn is 195.8 km. The road distance is 334 km.
You can take a train from Mainz, Römisches Theater to Paderborn Hbf via Frankfurt and Kassel-Wilhelmshoehe in around 4h 5m.