The average train between Mainz and Hamburg takes 4h 59m and the fastest train takes 4h 22m. There is a train service every few hours from Mainz to Hamburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Hamburg. The earliest departure is at 4:34 AM at night, and the last departure from Mainz is at 10:35 PM which arrives into Hamburg at 6:50 AM. All services require a transfer, and take on average 4h 59m. The schedules shown below are for the next available departures.

4h 55m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 42m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 42m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 42m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 42m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 55m • 1 change
4h 42m • 1 change
4h 54m • 1 change
4h 54m • 1 change
4h 54m • 1 change
4h 54m • 1 change
4h 54m • 1 change
4h 54m • 1 change
4h 54m • 1 change
4h 54m • 1 changeWant to know about travelling from Mainz to Hamburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Hamburg. However, there are services departing from Frankfurt station and arriving at Hamburg Hbf station via Hamburg Hbf station. The journey, including transfers, takes approximately 4h 59m.
Mainz to Hamburg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Mainz to Hamburg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hamburg Hbf station.
Book your Mainz to Hamburg train tickets online with Omio.
The distance between Mainz and Hamburg is 413.7 km. The road distance is 509 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Hamburg Hbf hourly. Tickets cost €90–200 and the journey takes 3h 43m.