The average train between Mainz and Ghent takes 5h 21m and the fastest train takes 4h 51m. The train service runs several times per day from Mainz to Ghent. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Ghent. The earliest departure is at 3:49 AM at night, and the last departure from Mainz is at 7:20 PM which arrives into Ghent at 12:19 AM. All services require a transfer at Köln Hbf and take an average of 5h 21m. The schedules shown below are for the next available departures.


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4h 59m • 2 changesWant to know about travelling from Mainz to Ghent? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Ghent. However, there are services departing from Mainz, Hauptbahnhof station and arriving at Gand-Saint-Pierre station via Köln Hbf station and Bruxelles Midi station. The journey, including transfers, takes approximately 5h 21m.
Mainz to Ghent train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
Mainz to Ghent train services, operated by Belgian Railways (NMBS/SNCB), arrive at Gand-Saint-Pierre station.
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The distance between Mainz and Ghent is 343.6 km. The road distance is 424 km.
You can take a train from Mainz, Hauptbahnhof to Gand-Saint-Pierre via Köln Hbf, Bruxelles Midi, and Bruxelles-Midi in around 4h 59m.