The average train between Mainz and Neuss takes 2h 26m and the fastest train takes 1h 52m. There is a train service every few hours from Mainz to Neuss. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Neuss. The earliest departure is at 5:09 AM in the morning, and the last departure from Mainz is at 11:14 PM which arrives into Neuss at 8:06 AM. All services require a transfer at Frankfurt and take an average of 2h 26m. The schedules shown below are for the next available departures.


2h 32m • 2 changes


1h 52m • 2 changes


2h 32m • 2 changes


1h 52m • 2 changes


2h 57m • 2 changes


1h 53m • 2 changes


2h 19m • 2 changes


1h 52m • 2 changes


2h 57m • 2 changes


1h 53m • 2 changes


2h 19m • 2 changes


1h 52m • 2 changes
Want to know about travelling from Mainz to Neuss? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Neuss. However, there are services departing from Mainz station and arriving at Neuss station via Frankfurt. The journey, including transfers, takes approximately 2h 26m.
Mainz to Neuss train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Neuss train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Neuss Hbf station.
Book your Mainz to Neuss train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Neuss is 175.7 km. The road distance is 230 km.
You can take a train from Mainz, Römisches Theater to Neuss Hbf via Frankfurt, Köln Messe/Deutz Bf, and Koeln Messe/Deutz in around 2h 16m.