The average train between Mainz and Neuss takes 2h 19m and the fastest train takes 1h 52m. There is a train service every few hours from Mainz to Neuss. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Neuss. The earliest departure is at 5:09 AM in the morning, and the last departure from Mainz is at 8:35 PM which arrives into Neuss at 11:06 PM. All services require a transfer at Frankfurt and take an average of 2h 19m. The schedules shown below are for the next available departures.


1h 53m • 2 changes


2h 19m • 2 changes


1h 52m • 2 changes


2h 32m • 2 changes


2h 57m • 2 changes


1h 53m • 2 changes


2h 19m • 2 changes


1h 52m • 2 changes


2h 1m • 2 changes


1h 52m • 2 changes


1h 52m • 2 changes


1h 52m • 2 changes


1h 52m • 2 changes


1h 52m • 2 changes


1h 52m • 2 changes


2h 19m • 2 changes
Want to know about travelling from Mainz to Neuss? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Neuss. However, there are services departing from Mainz station and arriving at Neuss station via Frankfurt. The journey, including transfers, takes approximately 2h 19m.
Mainz to Neuss train services, operated by vlexx, depart from Mainz, Römisches Theater station.
Mainz to Neuss train services, operated by vlexx, arrive at Neuss Hbf station.
Book your Mainz to Neuss train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Neuss is 175.7 km. The road distance is 230 km.
You can take a train from Mainz, Römisches Theater to Neuss Hbf via Frankfurt, Köln Messe/Deutz Bf, and Koeln Messe/Deutz in around 2h 17m.