The average train between Mainz and Leverkusen takes 2h 38m and the fastest train takes 2h 24m. The train service runs several times per day from Mainz to Leverkusen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Leverkusen. The earliest departure is at 3:49 AM at night, and the last departure from Mainz is at 8:19 PM which arrives into Leverkusen at 10:45 PM. All services require a transfer, and take on average 2h 38m. The schedules shown below are for the next available departures.

2h 55m • 1 change

3h 41m • 1 change

2h 27m • 1 change

2h 24m • 1 change

3h 55m • 1 change

2h 27m • 1 change

2h 24m • 1 change

2h 24m • 1 change

4h 55m • 1 change

2h 27m • 1 change

2h 24m • 1 change

2h 24m • 1 change

2h 55m • 1 change

3h 41m • 1 change

2h 27m • 1 change

2h 24m • 1 change

2h 55m • 1 change

3h 41m • 1 change

2h 27m • 1 change

2h 24m • 1 change
Want to know about travelling from Mainz to Leverkusen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Leverkusen. However, there are services departing from Mainz station and arriving at Leverkusen station via Koblenz Hbf. The journey, including transfers, takes approximately 2h 38m.
Mainz to Leverkusen train services, operated by Nederlandse Spoorwegen (NS), depart from Mainz Hbf station.
Mainz to Leverkusen train services, operated by Nederlandse Spoorwegen (NS), arrive at Leverkusen Mitte station.
Book your Mainz to Leverkusen train tickets online with Nederlandse Spoorwegen (NS), National Express and 2 other operators.
The distance between Mainz and Leverkusen is 148 km. The road distance is 194 km.
You can take a train from Mainz Hbf to Leverkusen Mitte via Koblenz Hbf in around 2h 35m.