There are 8 ways to get from Mainz to Lyon by plane, train, bus, car, or train (TGV)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Lyon–Saint Exupéry Airport
best- Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)FRA - LYS
4h 30m€122–247Bus via Saarbrücken
cheapest- Take the bus from Mainz central train station to Saarbrücken bus stationN90 / ...
- Take the bus from Saarbrücken bus station to LyonN235
10h 5m€39–67Train
- Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhofS5 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof82 / ...
- Take the train from Strasbourg Bahnhof to Lyon Part Dieu84
8h 6m€94–345Drive 652.7 km
- Drive from Mainz to Lyon652.7 km
5h 59m€101–146Fly Frankfurt to Geneva International Airport, train
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)FRA - GVA
- Take the train from Geneve to Lyon Part Dieu
6h 52m€135–331Train, train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)SXB - LYS
6h 43m€163–334Train via Strasbourg
- Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhofS5 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof82 / ...
- Take the train from Strasbourg to Lyon Part DieuTgv
8h 22m€94–285Bus
- Take the bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny A
11h 49m€74–99
Mainz to Lyon by train
Questions & Answers
The cheapest way to get from Mainz to Lyon is to bus via Saarbrücken which costs €35 - €70 and takes 10h 5m.
The fastest way to get from Mainz to Lyon is to fly which takes 4h 30m and costs €120 - €250.
No, there is no direct bus from Mainz station to Lyon. However, there are services departing from Mainz central train station and arriving at Lyon via Saarbrücken bus station. The journey, including transfers, takes approximately 10h 5m.
No, there is no direct train from Mainz to Lyon. However, there are services departing from Mainz, Römisches Theater and arriving at Lyon Part Dieu via Mannheim, Hauptbahnhof and Strasbourg Bahnhof. The journey, including transfers, takes approximately 8h 6m.
The distance between Mainz and Lyon is 595 km. The road distance is 652.7 km.
The best way to get from Mainz to Lyon without a car is to train which takes 8h 6m and costs €90 - €350.
It takes approximately 4h 30m to get from Mainz to Lyon, including transfers.
Mainz to Lyon bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Lyon train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
The best way to get from Mainz to Lyon is to fly which takes 4h 30m and costs €120 - €250. Alternatively, you can train, which costs €90 - €350 and takes 8h 6m, you could also bus via Saarbrücken, which costs €35 - €70 and takes 10h 5m.
What companies run services between Mainz, Germany and Lyon, France?
Lufthansa and Air Dolomiti fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS) every 4 hours. Alternatively, you can take a train from Mainz, Römisches Theater to Lyon Part Dieu via Mannheim, Hauptbahnhof and Strasbourg Bahnhof in around 8h 6m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- lufthansa.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €90–330
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Monday to Friday
- Estimated price
- €90–210
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €65–430
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €70–430
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €65–430
Flights from Frankfurt to Geneva International Airport via Zurich
- Ave. Duration
- 2h 52m
- When
- Every day
- Estimated price
- €65–430
- Website
- airdolomiti.it
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €100–330
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €95–320
- Website
- twinjet.fr
Flights from Strasbourg International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €430–900
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Every 30 minutes
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €35–65
- Website
- https://int.bahn.de/en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Strasbourg Bahnhof to Lyon Part Dieu
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €45–260
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Geneve to Lyon Part Dieu
- Ave. Duration
- 2h 8m
- Frequency
- Twice a week
- Estimated price
- €25–35
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Geneve to Lyon Part Dieu
- Ave. Duration
- 1h 50m
- Frequency
- 6 times a week
- Estimated price
- €40–85
- Website
- https://www.sncf-connect.com/en-en
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 3h 58m
- Frequency
- 5 times a day
- Estimated price
- €45–200
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +352 24 89 24 89
- Website
- cfl.lu
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 3h 55m
- Frequency
- Twice daily
- Estimated price
- €120–190
- Website
- https://www.cfl.lu/en-gb
- 1st Class
- €120–190
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Mainz central train station to Saarbrücken bus station
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- €9–12
- Website
- https://www.flixbus.co.uk
Bus from Saarbrücken bus station to Lyon
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
- Phone
- +48 801 22 33 44
- bilety@sindbad.pl
- Website
- sindbad.pl
Bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny A
- Ave. Duration
- 10h 10m
- Frequency
- Twice a week
- Estimated price
- €65–85
- Website
- https://www.sindbad.pl/en/home
Want to know more about travelling around France
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More Questions & Answers
Mainz to Lyon bus services, operated by FlixBus, arrive at Saarbrücken bus station.
Mainz to Lyon train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lyon is 653 km. It takes approximately 5h 59m to drive from Mainz to Lyon.
Book your Mainz to Lyon train tickets online with Omio.
Book your Mainz to Lyon bus tickets online with Omio and FlixBus.
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