Rome2Rio

How to get fromMainz to Lyonby plane, train (TGV), train, bus, or car

Find Transport to Lyon

See all options

There are 5 ways to get from Mainz to Lyon by plane, train (TGV), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    4h 29m
    €131–346

  2. Train, bus

    cheapest
    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the bus from Mannheim - Bus Station to Lyon - Gerland Bus Stationbus bus BlaBlaCar Bus
    11h 20m
    €58–137

  3. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train 82 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    8h 36m
    €123–257

  4. Drive  652.8 km

    1. Drive from Mainz to Lyoncar car 652.8 km
    6h 2m
    €105–151

  5. Bus

    1. Take the bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny Abus bus
    11h 35m
    €111–171

Mainz to Lyon by train

Calendar28Weekly Trains
Duration8h 36mAverage Duration
Ticket€123Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mainz to Lyon.ExpandLaunch map view
  • Distance: 594.8 km
  • Duration: 4h 29m

What companies run services between Mainz, Germany and Lyon, France?

Lufthansa, Airbus France, and three other airlines fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS) 5 times a day. Alternatively, you can take a train from Mainz, Römisches Theater to Lyon Part Dieu via Mannheim, Hauptbahnhof, Strasbourg Bahnhof, and Strasbourg in around 8h 36m.

Airlines
Train operators
Bus operators

Want to know more about travelling around France

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Booking & Getting There