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How to get fromMainz to Lyonby plane, train (TGV), bus, or car

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There are 6 ways to get from Mainz to Lyon by plane, train (TGV), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    4h 30m
    €132–258

  2. Bus via Frankfurt

    cheapest
    1. Take the bus from Frankfurt - Airport Bus Station to Lyon - Gerland Bus Stationbus bus BlaBlaCar Bus
    13h 10m
    €65–126

  3. Train via Offenburg

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Offenburg Bahnhoftrain train 12 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    8h 19m
    €127–416

  4. Bus

    1. Take the bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny Abus bus
    11h 49m
    €74–166

  5. Drive 652.8 km

    1. Drive from Mainz to Lyoncar car 652.8 km
    6h 2m
    €101–145

  6. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train 82 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    8h 38m
    €140–318

Mainz to Lyon by train

Calendar62Weekly Trains
Duration8h 19mAverage Duration
Ticket€127Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Lyon.ExpandLaunch map view
  • Distance: 594.8 km
  • Duration: 4h 30m

What companies run services between Mainz, Germany and Lyon, France?

Lufthansa, Air Dolomiti, and two other airlines fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS) every 4 hours. Alternatively, you can take a train from Mainz, Hauptbahnhof to Lyon Part Dieu via Mannheim, Hauptbahnhof, Offenburg Bahnhof, Strasbourg Bahnhof, and Strasbourg in around 8h 19m.

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