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How to get fromMainz to Lyonby plane, train, bus, car, or train (TGV)

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There are 7 ways to get from Mainz to Lyon by plane, train, bus, car, or train (TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Frankfurt

    best
    1. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    4h 29m
    €141–308

  2. Bus

    cheapest
    1. Take the bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny Abus bus
    12h
    €68–134

  3. Train

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train 82 / ...
    3. Take the train from Strasbourg Bahnhof to Lyon Part Dieutrain train 84
    7h 31m
    €113–280

  4. Train, bus

    1. Take the train from Mainz, Römisches Theater to Ludwigshafen, Mittetrain train S5 / ...
    2. Take the train from Ludwigshafen, Mitte to Karlsruhe Hauptbahnhoftrain train S3 / ...
    3. Take the bus from Karlsruhe central train station to Lyonbus bus
    11h 51m
    €69–119

  5. Drive 652.8 km

    1. Drive from Mainz to Lyoncar car 652.8 km
    6h 2m
    €103–149

  6. Train, train to Strasbourg International Airport, fly

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train
    3. Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane plane SXB - LYS
    6h 7m
    €160–389

  7. Train via Mainz, Römisches Theater

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train 82 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    8h 24m
    €149–276

Mainz to Lyon by train

Calendar7Weekly Trains
Duration7h 31mAverage Duration
Ticket€113Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Lyon.ExpandLaunch map view
  • Distance: 594.8 km
  • Duration: 4h 29m

What companies run services between Mainz, Germany and Lyon, France?

Lufthansa, Air Dolomiti, and Lufthansa City fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS) 5 times a day. Alternatively, you can take a train from Mainz, Hauptbahnhof to Lyon Part Dieu via Mannheim, Hauptbahnhof and Strasbourg Bahnhof in around 7h 31m.

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