There are 6 ways to get from Mainz to Lyon by plane, train (TGV), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane FRA - LYS
4h 30m€142–318Bus via Frankfurt
cheapest- Take the bus from Frankfurt - Airport Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
13h 9m€55–117Train via Mannheim
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Lyon Part Dieutrain Tgv
8h 24m€140–256Bus
- Take the bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny Abus
11h 49m€68–144Drive 652.8 km
- Drive from Mainz to Lyoncar 652.8 km
6h 2m€101–146Train
- Take the train from Frankfurt to Offenburg Bahnhoftrain 20 / ...
- Take the train from Strasbourg Bahnhof to Lyon Part Dieutrain 84
8h 41m€124–344
Mainz to Lyon by train
Questions & Answers
The cheapest way to get from Mainz to Lyon is to bus via Frankfurt which costs €55 - €120 and takes 13h 9m.
The fastest way to get from Mainz to Lyon is to fly which takes 4h 30m and costs €140 - €320.
No, there is no direct bus from Mainz to Lyon station. However, there are services departing from Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus and arriving at Lyon - Gerland Bus Station via Frankfurt - Airport Bus Station. The journey, including transfers, takes approximately 13h 9m.
No, there is no direct train from Mainz to Lyon. However, there are services departing from Mainz, Römisches Theater and arriving at Lyon Part Dieu via Mannheim, Hauptbahnhof and Strasbourg. The journey, including transfers, takes approximately 8h 24m.
The distance between Mainz and Lyon is 595 km. The road distance is 652.8 km.
The best way to get from Mainz to Lyon without a car is to train via Mannheim which takes 8h 24m and costs €140 - €260.
It takes approximately 4h 30m to get from Mainz to Lyon, including transfers.
Mainz to Lyon bus services, operated by BlaBlaCar Bus, depart from Frankfurt - Airport Bus Station.
Mainz to Lyon train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
The best way to get from Mainz to Lyon is to fly which takes 4h 30m and costs €140 - €320. Alternatively, you can train via Mannheim, which costs €140 - €260 and takes 8h 24m, you could also bus, which costs €65 - €150 and takes 11h 49m.
What companies run services between Mainz, Germany and Lyon, France?
Lufthansa, Air Dolomiti, and Lufthansa City fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS) 5 times a day. Alternatively, you can take a train from Mainz, Römisches Theater to Lyon Part Dieu via Mannheim, Hauptbahnhof, Strasbourg Bahnhof, and Strasbourg in around 8h 24m.
- Website
- lufthansa.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €95–600
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €60–350
- Website
- airdolomiti.it
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €130–600
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €14–21
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Once daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €26–65
- Website
- https://int.bahn.de/en
Train from Frankfurt to Offenburg Bahnhof
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €35–90
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 3h 58m
- Frequency
- Every 4 hours
- Estimated price
- €100–170
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Strasbourg Bahnhof to Lyon Part Dieu
- Ave. Duration
- 3h 43m
- Frequency
- Once daily
- Estimated price
- €75–170
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +48 801 22 33 44
- bilety@sindbad.pl
- Website
- sindbad.pl
Bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny A
- Ave. Duration
- 10h 10m
- Frequency
- Twice a week
- Estimated price
- €60–130
- Website
- https://www.sindbad.pl/en/home
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Frankfurt - Airport Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 11h 15m
- Frequency
- Every 3 hours
- Estimated price
- €55–110
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Frankfurt - Airport Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 9h 35m
- Frequency
- Twice daily
- Estimated price
- €50–95
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around France
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More Questions & Answers
Mainz to Lyon bus services, operated by BlaBlaCar Bus, arrive at Lyon - Gerland Bus Station.
Mainz to Lyon train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lyon is 653 km. It takes approximately 6h 2m to drive from Mainz to Lyon.
Book your Mainz to Lyon train tickets online with Omio.
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