Mainz to Lucerne Trains

Trip Overview

The average train between Mainz and Lucerne takes 5h 7m and the fastest train takes 4h 19m. There is a train service every few hours from Mainz to Lucerne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 7m
Duration: 416 km
Distance: CHF 106
Average price: Hourly
Frequency

Train via Basel

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luzerntrain Ec / ...

CHF 63–285

Mainz to Lucerne train times

Trains run hourly between Mainz and Lucerne. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Lucerne at 8:05 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 5h 7m. The schedules shown below are for the next available departures.

Departing Saturday, September 12, 2026

9:13 AM → 2:05 PM
4h 52m • 2 changes
11:17 AM → 4:05 PM
4h 48m • 2 changes
12:42 PM → 5:05 PM
4h 23m • 2 changes
1:13 PM → 6:05 PM
4h 52m • 2 changes
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Departing Sunday, September 13, 2026

1:38 AM → 8:05 AM
6h 27m • 2 changes
5:40 AM → 10:05 AM
4h 25m • 2 changes
6:56 AM → 12:05 PM
5h 9m • 2 changes
8:42 AM → 1:05 PM
4h 23m • 2 changes
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Departing Monday, September 14, 2026

5:40 AM → 10:05 AM
4h 25m • 2 changes
5:52 AM → 11:05 AM
5h 13m • 2 changes
7:46 AM → 12:05 PM
4h 19m • 2 changes
8:42 AM → 1:05 PM
4h 23m • 2 changes
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Departing Tuesday, September 15, 2026

5:40 AM → 10:05 AM
4h 25m • 2 changes
5:52 AM → 11:05 AM
5h 13m • 2 changes
7:46 AM → 12:05 PM
4h 19m • 2 changes
8:42 AM → 1:05 PM
4h 23m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Mainz to Lucerne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.