There are 7 ways to get from Mainz to Lucerne by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Basel
best- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luzerntrain Ec / ...
5h 1mCHF 60–153Bus
cheapest- Take the bus from Mainz central train station to Saarbrücken bus stationbus N90 / ...
- Take the bus from Saarbrücken bus station to Luzernbus FlixBus N846
8hCHF 38–62Drive 420.7 km
- Drive from Mainz to Lucernecar 420.7 km
3h 38mCHF 71–102Fly Frankfurt to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich HB to Luzerntrain
3h 25mCHF 107–235Train
- Take the train from Mainz Hbf to Zürich HBtrain Nightjet
- Take the train from Zürich HB to Luzerntrain Ir70 / ...
7h 24mCHF 63–117Fly Frankfurt to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Luzerntrain
4h 20mCHF 143–338Train to Stuttgart Airport, fly to Zurich Airport, train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Zurich Airport (ZRH)plane STR - ZRH
- Take the train from Zürich HB to Luzerntrain
5h 14mCHF 147–355
Mainz to Lucerne by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Lucerne is to bus which costs SFr 35 - SFr 65 and takes 8h.
The fastest way to get from Mainz to Lucerne is to fly and train which takes 3h 25m and costs SFr 100 - SFr 240.
No, there is no direct bus from Mainz station to Lucerne. However, there are services departing from Mainz central train station and arriving at Luzern via Saarbrücken bus station. The journey, including transfers, takes approximately 8h.
No, there is no direct train from Mainz to Lucerne. However, there are services departing from Mainz, Hauptbahnhof and arriving at Luzern via Mannheim, Hauptbahnhof and Basel SBB. The journey, including transfers, takes approximately 5h 1m.
The distance between Mainz and Lucerne is 416 km. The road distance is 420.7 km.
The best way to get from Mainz to Lucerne without a car is to train via Basel which takes 5h 1m and costs SFr 60 - SFr 160.
It takes approximately 5h 1m to get from Mainz to Lucerne, including transfers.
Mainz to Lucerne bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Lucerne is to train via Basel which takes 5h 1m and costs SFr 60 - SFr 160. Alternatively, you can bus, which costs SFr 35 - SFr 65 and takes 8h.
What companies run services between Mainz, Germany and Lucerne, Switzerland?
You can take a train from Mainz, Hauptbahnhof to Luzern via Mannheim, Hauptbahnhof and Basel SBB in around 5h 1m. Alternatively, you can take a bus from Mainz central train station to Luzern via Saarbrücken bus station in around 8h.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- CHF 80–430
Flights from Frankfurt to Basel
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- CHF 75–450
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 40m
- When
- Monday, Friday, Wednesday, Thursday, and Saturday
- Estimated price
- CHF 45–280
Flights from Stuttgart Airport to Zurich Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- CHF 60–410
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 12–24
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- CHF 40–85
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–60
- Website
- Deutsche Bahn Intercity (DB IC)
#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Mainz central train station to Saarbrücken bus station
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- CHF 11–17
- Website
- Flixbus
Bus from Saarbrücken bus station to Luzern
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a week
- Estimated price
- CHF 27–45
- Website
- Flixbus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Booking & Getting There
Mainz to Lucerne bus services, operated by FlixBus, arrive at Saarbrücken bus station.
Mainz to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lucerne is 421 km. It takes approximately 3h 38m to drive from Mainz to Lucerne.
Book your Mainz to Lucerne train tickets online with Omio.
Book your Mainz to Lucerne bus tickets online with Omio and FlixBus.
There are 672+ hotels available in Lucerne.