There are 7 ways to get from Mainz to Lucerne by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luzerntrain Ec / ...
5hCHF 62–176Bus
cheapest- Take the bus from Mainz central train station to Saarbrücken bus stationbus N90 / ...
- Take the bus from Saarbrücken bus station to Luzernbus FlixBus N846
8hCHF 40–62Night train, train
- Take the nighttrain from Mainz Hbf to Zuerich Hbnighttrain Nj
- Take the train from Zürich HB to Luzerntrain Ir70 / ...
7h 20mCHF 47–119Drive 420.7 km
- Drive from Mainz to Lucernecar 420.7 km
3h 38mCHF 70–102Fly Frankfurt to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich HB to Luzerntrain
3h 25mCHF 115–249Fly Frankfurt to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Luzerntrain
4h 20mCHF 145–391Train to Stuttgart Airport, fly to Zurich Airport, train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Zurich Airport (ZRH)plane STR - ZRH
- Take the train from Zürich HB to Luzerntrain
5h 14mCHF 152–365
Mainz to Lucerne by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Lucerne is to bus which costs SFr 35 - SFr 65 and takes 8h.
The fastest way to get from Mainz to Lucerne is to fly and train which takes 3h 25m and costs SFr 110 - SFr 250.
No, there is no direct bus from Mainz station to Lucerne. However, there are services departing from Mainz central train station and arriving at Luzern via Saarbrücken bus station. The journey, including transfers, takes approximately 8h.
No, there is no direct train from Mainz to Lucerne. However, there are services departing from Mainz, Hauptbahnhof and arriving at Luzern via Mannheim, Hauptbahnhof and Basel SBB. The journey, including transfers, takes approximately 5h.
The distance between Mainz and Lucerne is 416 km. The road distance is 420.7 km.
The best way to get from Mainz to Lucerne without a car is to train which takes 5h and costs SFr 60 - SFr 180.
It takes approximately 5h to get from Mainz to Lucerne, including transfers.
Mainz to Lucerne bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Lucerne is to train which takes 5h and costs SFr 60 - SFr 180. Alternatively, you can bus, which costs SFr 35 - SFr 65 and takes 8h.
What companies run services between Mainz, Germany and Lucerne, Switzerland?
You can take a train from Mainz, Hauptbahnhof to Luzern via Mannheim, Hauptbahnhof and Basel SBB in around 5h. Alternatively, you can take a bus from Mainz central train station to Luzern via Saarbrücken bus station in around 8h.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–350
Flights from Frankfurt to Basel
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 75–420
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 75–420
Flights from Stuttgart Airport to Zurich Airport
- Ave. Duration
- 45 min
- When
- Saturday
- Estimated price
- CHF 60–340
- Website
- swiss.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–350
Flights from Frankfurt to Basel
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- CHF 75–420
Flights from Stuttgart Airport to Zurich Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- CHF 60–340
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 90–200
- Website
- airdolomiti.it
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 120–350
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 130–380
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 11–24
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- CHF 40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- CHF 28–65
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- CHF 10–45
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- CHF 13–19
- Schedules at
- Süwex
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- CHF 7–14
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- CHF 25–50
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- CHF 45–95
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 30–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 18–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 18–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 30–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 18–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +41 58 580 70 70
- Website
- Schweizerische Südostbahn AG
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–45
- Schedules at
- Schweizerische Südostbahn AG
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–45
- Schedules at
- Schweizerische Südostbahn AG
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- 3 times a week
- Estimated price
- CHF 29–93
- Website
- Nightjet
- Sleeper Carriage
- CHF 90–93
- Couchette Carriage
- CHF 55–70
- Seating Carriage
- CHF 29–35
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Mainz central train station to Saarbrücken bus station
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- CHF 11–18
- Website
- Flixbus
Bus from Saarbrücken bus station to Luzern
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a week
- Estimated price
- CHF 28–45
- Website
- Flixbus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Mainz to Lucerne bus services, operated by FlixBus, arrive at Saarbrücken bus station.
Mainz to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Lucerne is 421 km. It takes approximately 3h 38m to drive from Mainz to Lucerne.
Book your Mainz to Lucerne train tickets online with Omio.
Book your Mainz to Lucerne bus tickets online with Omio and FlixBus.
There are 666+ hotels available in Lucerne.

































