There are 8 ways to get from Mainz to Lucerne by train, bus, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Frankfurt to Basel SBBtrain 43
- Take the train from Basel SBB to Luzerntrain Ic21 / ...
5h 30mCHF 79–146Bus
cheapest- Take the bus from Mainz central train station to Saarbrücken bus stationbus N90 / ...
- Take the bus from Saarbrücken bus station to Luzernbus FlixBus N846
8hCHF 41–63Night train, train
- Take the nighttrain from Mainz Hbf to Zuerich Hbnighttrain Nj
- Take the train from Zürich HB to Luzerntrain Ir70 / ...
7h 20mCHF 45–118Drive 420.7 km
- Drive from Mainz to Lucernecar 420.7 km
3h 38mCHF 75–108Train via Mannheim
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luzerntrain Ec / ...
5h 39mCHF 75–133Fly Frankfurt to Zurich Airport, train
- Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane FRA - ZRH
- Take the train from Zürich HB to Luzerntrain
3h 25mCHF 113–245Fly Frankfurt to Basel, train
- Fly from Frankfurt (FRA) to Basel (BSL)plane FRA - BSL
- Take the train from Basel SBB to Luzerntrain
4h 20mCHF 155–387Train to Stuttgart Airport, fly to Zurich Airport, train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Zurich Airport (ZRH)plane STR - ZRH
- Take the train from Zürich HB to Luzerntrain
5h 14mCHF 158–376
Mainz to Lucerne by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Lucerne is to bus which costs SFr 40 - SFr 65 and takes 8h.
The fastest way to get from Mainz to Lucerne is to fly and train which takes 3h 25m and costs SFr 110 - SFr 250.
No, there is no direct bus from Mainz station to Lucerne. However, there are services departing from Mainz central train station and arriving at Luzern via Saarbrücken bus station. The journey, including transfers, takes approximately 8h.
No, there is no direct train from Mainz to Lucerne. However, there are services departing from Mainz, Römisches Theater and arriving at Luzern via Frankfurt and Basel SBB. The journey, including transfers, takes approximately 5h 30m.
The distance between Mainz and Lucerne is 444 km. The road distance is 420.7 km.
The best way to get from Mainz to Lucerne without a car is to train which takes 5h 30m and costs SFr 75 - SFr 150.
It takes approximately 5h 30m to get from Mainz to Lucerne, including transfers.
Mainz to Lucerne bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Lucerne is to train which takes 5h 30m and costs SFr 75 - SFr 150. Alternatively, you can bus, which costs SFr 40 - SFr 65 and takes 8h.
What companies run services between Mainz, Germany and Lucerne, Switzerland?
You can take a train from Mainz, Römisches Theater to Luzern via Frankfurt and Basel SBB in around 5h 30m. Alternatively, you can take a bus from Mainz central train station to Luzern via Saarbrücken bus station in around 8h.
- Website
- lufthansa.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 70–400
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–460
Flights from Frankfurt to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- CHF 75–420
- Website
- swiss.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 70–400
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 75–420
Flights from Stuttgart Airport to Zurich Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- CHF 60–330
- Website
- condor.com
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- CHF 90–210
- Website
- airdolomiti.it
Flights from Frankfurt to Zurich Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 130–400
Flights from Frankfurt to Basel
- Ave. Duration
- 55 min
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 150–460
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- CHF 45–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- CHF 35–70
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- CHF 26–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 28–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 16–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 28–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 16–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- CHF 28–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Luzern
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 16–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +41 58 580 70 70
- Website
- Schweizerische Südostbahn AG
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–45
- Schedules at
- Schweizerische Südostbahn AG
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–45
- Schedules at
- Schweizerische Südostbahn AG
Train from Basel SBB to Luzern
- Ave. Duration
- 1h 1m
- Frequency
- Every 4 hours
- Estimated price
- CHF 30–45
- Schedules at
- Schweizerische Südostbahn AG
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- Twice daily
- Estimated price
- CHF 45–85
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- 6 times a week
- Estimated price
- CHF 29–93
- Website
- Nightjet
- Sleeper Carriage
- CHF 89–93
- Couchette Carriage
- CHF 55–70
- Seating Carriage
- CHF 29–35
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- CHF 10
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- CHF 13–19
- Schedules at
- Süwex
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Mainz central train station to Saarbrücken bus station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- CHF 12–18
- Website
- Flixbus
Bus from Saarbrücken bus station to Luzern
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a week
- Estimated price
- CHF 29–45
- Website
- Flixbus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Mainz to Lucerne bus services, operated by FlixBus, arrive at Saarbrücken bus station.
Mainz to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mainz to Lucerne is 421 km. It takes approximately 3h 38m to drive from Mainz to Lucerne.
Book your Mainz to Lucerne train tickets online with Omio.
Book your Mainz to Lucerne bus tickets online with Omio and FlixBus.
There are 661+ hotels available in Lucerne.







































