The average train between Mainz and Leiden takes 5h 30m and the fastest train takes 4h 33m. The train service runs several times per day from Mainz to Leiden. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Leiden. The earliest departure is at 4:04 AM at night, and the last departure from Mainz is at 11:04 PM which arrives into Leiden at 9:32 AM. All services require a transfer at Frankfurt and take an average of 5h 30m. The schedules shown below are for the next available departures.



5h 58m • 3 changes



4h 49m • 3 changes



4h 48m • 3 changes



4h 48m • 3 changes



5h 58m • 3 changes



4h 49m • 3 changes



4h 48m • 3 changes



4h 48m • 3 changes



5h 43m • 3 changes



4h 49m • 3 changes



4h 48m • 3 changes



4h 33m • 3 changes



5h 43m • 3 changes



4h 49m • 3 changes



4h 48m • 3 changes



4h 33m • 3 changes



5h 58m • 3 changes



4h 49m • 3 changes



4h 48m • 3 changes



4h 48m • 3 changes
Want to know about travelling from Mainz to Leiden? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Leiden. However, there are services departing from Mainz station and arriving at Leiden station via Düsseldorf Hbf. The journey, including transfers, takes approximately 5h 30m.
Mainz to Leiden train services, operated by vlexx, depart from Frankfurt station.
Mainz to Leiden train services, operated by vlexx, arrive at Leiden Lammenschans station.
Book your Mainz to Leiden train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Mainz and Leiden is 358.3 km. The road distance is 457 km.
You can take a train from Mainz, Römisches Theater to Leiden Lammenschans via Frankfurt, Düsseldorf Hbf, and Utrecht Centraal in around 5h 26m.