The average train between Mainz and Leiden takes 5h 46m and the fastest train takes 4h 59m. The train service runs several times per day from Mainz to Leiden. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Mainz and Leiden. The earliest departure is at 2:04 AM at night, and the last departure from Mainz is at 7:14 PM which arrives into Leiden at 7:45 AM. All services require a transfer at Frankfurt and take an average of 5h 46m. The schedules shown below are for the next available departures.


7h 39m • 2 changes

5h 9m • 2 changes

5h • 2 changes

5h • 2 changes

8h 11m • 2 changes

5h 9m • 2 changes

5h • 2 changes

5h • 2 changes

7h 18m • 2 changes

5h 4m • 2 changes

5h • 2 changes

4h 59m • 2 changesWant to know about travelling from Mainz to Leiden? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Leiden. However, there are services departing from Mainz station and arriving at Leiden station via Arnhem Centraal. The journey, including transfers, takes approximately 5h 46m.
Mainz to Leiden train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Leiden train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Leiden Centraal station.
Book your Mainz to Leiden train tickets online with Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) and 2 other operators.
The distance between Mainz and Leiden is 358.3 km. The road distance is 484 km.
You can take a train from Mainz, Römisches Theater to Leiden Centraal via Frankfurt and Arnhem Centraal in around 5h 28m.