The average train between Mainz and Berlin takes 5h 18m and the fastest train takes 4h 34m. There is a train service every few hours from Mainz to Berlin. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Berlin. The earliest departure is at 2:04 AM at night, and the last departure from Mainz is at 11:14 PM which arrives into Berlin at 8:06 AM. All services require a transfer, and take on average 5h 18m. The schedules shown below are for the next available departures.

5h 31m • 1 change
5h 28m • 1 change
4h 40m • 1 change
5h 28m • 1 change
4h 40m • 1 change
5h 28m • 1 change
4h 40m • 1 change
4h 59m • 1 change
6h 2m • 1 change
5h 24m • 1 change
5h 3m • 1 change
5h 20m • 1 changeWant to know about travelling from Mainz to Berlin? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Berlin. However, there are services departing from Mainz station and arriving at Berlin station via Berlin Hbf. The journey, including transfers, takes approximately 5h 18m.
Mainz to Berlin train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Mainz to Berlin train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Berlin Hbf station.
Book your Mainz to Berlin train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Mainz and Berlin is 455.1 km. The road distance is 549 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Berlin Hbf hourly. Tickets cost €90–190 and the journey takes 4h 2m.