The average bus between London and Prescot takes 7h 32m and the fastest bus takes 6h 26m. There is a bus service every few hours from London to Prescot. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between London and Prescot. The earliest departure is at 2:00 AM at night, and the last departure from London is at 11:30 PM which arrives into Prescot at 6:56 AM. All services require a transfer, and take on average 7h 32m. The schedules shown below are for the next available departures.

6h 26m • 1 change
Arrives next day

7h 38m • 1 change
Arrives next day

11h 4m • 1 change
Arrives next day

7h 30m • 1 change

7h 43m • 1 change

6h 40m • 1 change

6h 58m • 1 change

7h 22m • 1 change

7h 43m • 1 change

6h 40m • 1 change

6h 58m • 1 change

7h 22m • 1 change

7h 43m • 1 change

6h 40m • 1 change

6h 58m • 1 change

7h 22m • 1 change

7h 43m • 1 change

6h 40m • 1 change

6h 58m • 1 change

7h 22m • 1 change
Want to know about travelling from London to Prescot? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from London to Prescot. However, there are services departing from London station and arriving at Prescot station via Liverpool, Liverpool One. The journey, including transfers, takes approximately 7h 32m.
London to Prescot bus services, operated by FlixBus, depart from London Victoria station.
London to Prescot bus services, operated by FlixBus, arrive at Liverpool, Liverpool One station.
The distance between London and Prescot is 280.1 km. The road distance is 358 km.
FlixBus operates a bus from London Victoria to Liverpool, Liverpool One every 4 hours. Tickets cost £21–40 and the journey takes 5h 35m. National Express also services this route hourly.