The average train between Brno and Mainz takes 13h 19m and the fastest train takes 11h 3m. The train service runs several times per day from Brno to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Brno and Mainz. The earliest departure is at 7:18 AM in the morning, and the last departure from Brno is at 10:18 PM which arrives into Mainz at 2:44 PM. All services require a transfer at Wien Hbf and take an average of 13h 19m. The schedules shown below are for the next available departures.
Arrives next day




14h 4m • 4 changes
Arrives next day




17h 26m • 4 changes




11h 3m • 4 changes




11h 3m • 4 changes
Arrives next day




14h 4m • 4 changes
Arrives next day




16h 26m • 4 changes
Want to know about travelling from Brno to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Brno to Mainz. However, there are services departing from Brno station and arriving at Mainz station via Wien Hbf. The journey, including transfers, takes approximately 13h 19m.
Brno to Mainz train services, operated by RegioJet, depart from Brno Hlavni Nadrazi station.
Brno to Mainz train services, operated by RegioJet, arrive at Frankfurt station.
Book your Brno to Mainz train tickets online with RegioJet, ÖBB Intercity and 8 other operators.
The distance between Brno and Mainz is 606.4 km. The road distance is 1,044 km.
You can take a train from Brno Hlavni Nadrazi to Mainz, Römisches Theater via Wien Hbf, St.Poelten Hbf, Muenchen Hbf Gl.5-10, München Hbf, and Frankfurt in around 10h 49m.