The average train between Hesse and Brussels takes 3h 4m and the fastest train takes 3h 2m. The train service runs several times per day from Hesse to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Hesse and Brussels. The earliest departure is at 6:19 AM in the morning, and the last departure from Hesse is at 8:04 PM which arrives into Brussels at 11:26 PM. All services require a transfer, and take on average 3h 4m. The schedules shown below are for the next available departures.

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Want to know about travelling from Hesse to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Hesse to Brussels. However, there are services departing from Hesse station and arriving at Brussels station via Brussels-Nord. The journey, including transfers, takes approximately 3h 4m.
Hesse to Brussels train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Hesse to Brussels train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Brussels-Nord station.
The distance between Hesse and Brussels is 330.4 km. The road distance is 398 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Brussels-Nord every 4 hours. Tickets cost €75–180 and the journey takes 2h 52m.