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Cleveland to St. Louis trains

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Trip Overview

The average train between Cleveland and St. Louis takes 14h 33m and the fastest train takes 12h 48m. The train service runs several times per day from Cleveland to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 33m
Duration
620 mi
Distance
$400
Average price
Twice daily
Frequency

Cleveland to St. Louis train times

Trains run twice daily between Cleveland and St. Louis. The earliest departure is at 1:59 AM at night, and the last departure from Cleveland is at 4:03 AM which arrives into St. Louis at 7:25 PM. All services require a transfer, and take on average 14h 33m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    AmtrakAmtrak12h 52m • 1 change
  •  → 

    AmtrakAmtrak16h 22m • 1 change

Departing Saturday, October 31, 2026

  •  → 

    AmtrakAmtrak12h 52m • 1 change
  •  → 

    AmtrakAmtrak16h 22m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    AmtrakAmtrak12h 48m • 1 change

Departing Monday, November 2, 2026

  •  → 

    AmtrakAmtrak13h 52m • 1 change
  •  → 

    AmtrakAmtrak16h 22m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    AmtrakAmtrak12h 52m • 1 change
  •  → 

    AmtrakAmtrak16h 22m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    AmtrakAmtrak12h 52m • 1 change
  •  → 

    AmtrakAmtrak16h 22m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    AmtrakAmtrak12h 52m • 1 change
  •  → 

    AmtrakAmtrak16h 22m • 1 change

Frequently asked questions

Want to know about travelling from Cleveland to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cleveland to St. Louis.ExpandLaunch map view
  • Distance: 620 mi
  • Duration: 14h 33m

What companies run services between Cleveland, OH, USA and St. Louis, MO, USA?

You can take a train from Cleveland Amtrak to St. Louis via Chicago Union Station in around 12h 32m.

Operators