The average train between Chiasso and Siena takes 5h 41m and the fastest train takes 5h 6m. There is a train service every few hours from Chiasso to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Chiasso and Siena. The earliest departure is at 4:31 AM at night, and the last departure from Chiasso is at 6:31 PM which arrives into Siena at 7:55 AM. All services require a transfer at Milano Centrale and take an average of 5h 41m. The schedules shown below are for the next available departures.


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5h 7m • 2 changes


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5h 7m • 2 changes
Want to know about travelling from Chiasso to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Chiasso to Siena. However, there are services departing from Chiasso station and arriving at Siena station via Milano Centrale. The journey, including transfers, takes approximately 5h 41m.
Chiasso to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Chiasso station.
Chiasso to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Siena station.
Book your Chiasso to Siena train tickets online with Swiss Federal Railways (SBB CFF FFS), Trenitalia Frecce and Trenitalia.
The distance between Chiasso and Siena is 334 km. The road distance is 448 km.
You can take a train from Chiasso to Siena via Milano Centrale and Firenze S.M.N. in around 5h 40m.